Bulut Ezgi, Taştekin Ebru, Topuz Canberk, Öztürk Sevgi, Gökyer Ali
Trakya University School of Medicine, Edirne, Turkey.
Department of Pathology, Trakya University School of Medicine, Edirne, Turkey.
J Gastrointest Cancer. 2022 Dec;53(4):1135-1137. doi: 10.1007/s12029-021-00747-2. Epub 2021 Nov 16.
Skin metastases from gastric cancer are rare and usually occur very late in the course of the disease. The most common metastatic sites liver, the peritoneal surfaces, and the non regional or distant lymph nodes.
In this case we report the short-term survival of a 67-year-old man complined of multiple nodular lesions in various part of his skin. Histology showed a metastatic signet ring cell adenocarsinoma. Esophagogastroduodenoscopy was performed and a crater- like ulcer, about 3 cm in diameter, was observed on the anterior part of the stomach corpus distal. A biopsy specimen was obtained, and histopathological findings were consistent with gastric signet-ring cell carcinoma. XELOX chemotherapy regimen was initiated for the patient.
Skin metastasis of gastric adenocarcinoma is a rare condition with a poor prognosis. It may be the first manifestation of a clinically silent visceral cancer or may represent a recurrence of an internal malignancy.
胃癌皮肤转移罕见，通常在疾病病程晚期出现。最常见的转移部位是肝脏、腹膜表面以及非区域或远处淋巴结。
在此病例中，我们报告了一名67岁男性的短期生存情况，该患者主诉其皮肤各部位有多个结节性病变。组织学检查显示为转移性印戒细胞腺癌。进行了食管胃十二指肠镜检查，在胃体远端前部观察到一个直径约3 cm的火山口样溃疡。获取了活检标本，组织病理学结果与胃印戒细胞癌一致。为该患者启动了XELOX化疗方案。
胃腺癌皮肤转移是一种罕见疾病，预后较差。它可能是临床上无症状内脏癌的首发表现，也可能代表内部恶性肿瘤的复发。
