通过聚合酶链反应检测 SARS-CoV-2 在 COVID-19 中的应用：一项综合综述。
Detection of SARS-CoV-2 through pool testing for COVID-19: an integrative review.
机构信息
Universidade Federal de Minas Gerais, Programa de Pós-Graduação em Ciências da Saúde: Infectologia e Medicina Tropical, Belo Horizonte, MG, Brasil.
Universidade Federal de Minas Gerais, Faculdade de Medicina, Belo Horizonte, MG, Brasil.
出版信息
Rev Soc Bras Med Trop. 2021 Nov 12;54:e0276. doi: 10.1590/0037-8682-0276-2021. eCollection 2021.
INTRODUCTION
The pool testing technique optimizes the number of tests performed and reduces the delivery time of results, which is an interesting strategy for the health crisis caused by the COVID-19 pandemic. This integrative review investigated studies in which pool testing was carried out for epidemiological or screening purposes to analyze its clinical or cost effectiveness and assessed the applicability of this method in high-, middle-, and low-income countries.
METHODS
This integrative review used primary studies published in the MEDLINE, EMBASE, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS), and Cochrane Library databases.
RESULTS
A total of 435 studies were identified: 35.3% were carried out in Asia, 29.4% in Europe, 29.4% in North America, and 5.9% in Oceania.
CONCLUSIONS
This review suggests that pool testing in the general population may be a useful surveillance strategy to detect new variants of SARS-CoV-2 and to evaluate the period of immunogenicity and global immunity from vaccines.
简介
池化检测技术优化了检测数量并缩短了结果交付时间，这对于由 COVID-19 大流行引起的卫生危机来说是一个很有趣的策略。本综合评价研究了为流行病学或筛查目的而进行的池化检测，以分析其临床或成本效益，并评估该方法在高、中、低收入国家的适用性。
方法
本综合评价使用了在 MEDLINE、EMBASE、Literatura Latino-Americana e do Caribe em Ciências da Saúde（LILACS）和 Cochrane 图书馆数据库中发表的原始研究。
结果
共确定了 435 项研究：35.3%在亚洲进行，29.4%在欧洲，29.4%在北美，5.9%在大洋洲。
结论
本综述表明，对普通人群进行池化检测可能是一种有用的监测策略，可用于检测 SARS-CoV-2 的新变体，并评估疫苗的免疫原性和全球免疫期。
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