Department of Periodontology, Faculty of Dentistry, Istanbul Okan University, Istanbul, Turkey.
Department of Periodontology, Faculty of Dentistry, Kocaeli University, Kocaeli, Turkey.
Clin Oral Investig. 2022 Mar;26(3):2761-2770. doi: 10.1007/s00784-021-04252-5. Epub 2021 Nov 17.
Gingival unit graft (GUG) is defined as the modified form of free gingival graft. The aim of this study is to compare the clinical efficacy of GUG with connective tissue graft (SCTG) with respect to clinical periodontal parameters and patient comfort scores in gingival recessions.
Sixteen patients with bilateral recession type 1 (RT1) gingival recessions participated in this randomized and split-mouth study. Thirty-two defects received surgical treatment with SCTG or GUG. The recession defect coverage, periodontal measurements, and patient-reported outcomes (intra- and post-operative patient comfort, aesthetic satisfaction, and hypersensitivity) were evaluated at baseline and post-operative months 1, 3 and 6.
The favorable results were obtained in both study groups in gingival recession depth (RD), gingival recession width (RW), clinical attachment level (CAL), and keratinized tissue width (KTW). The average percentages of the recession defect coverage (RC) for GUG and SCTG group treatments after 6 months were 68.2 ± 33% and 76.4 ± 30.2%, respectively (p > 0.05). Although there was no significant difference between groups at post-operative 6 months (p > 0.05) in terms of RD, RW, CAL, RC, patient comfort, aesthetic satisfaction, and hypersensitivity parameters, the increase in KTW was significantly higher in GUG group (p < 0.05).
It was concluded that although both techniques were effective, GUG can be a convenient method for treatment of RT1 gingival recessions with inadequate KTW and (or) shallow vestibule depth.
According to the results of this study, GUG may be a preferred choice in localized gingival recessions with a lack of keratinized tissue. The trial registration number: NCT04637451.
牙龈单位移植(GUG)被定义为游离牙龈移植的改良形式。本研究旨在比较 GUG 与结缔组织移植(SCTG)在牙龈退缩方面的临床疗效,包括临床牙周参数和患者舒适度评分。
本研究纳入了 16 名双侧 1 型(RT1)牙龈退缩的患者,采用随机、双侧分牙设计。32 个缺损部位分别接受 SCTG 或 GUG 治疗。在基线和术后 1、3、6 个月评估了退缩缺陷覆盖、牙周测量和患者报告的结果(手术期间和术后的患者舒适度、美学满意度和过敏感度)。
两组患者的牙龈退缩深度(RD)、牙龈退缩宽度(RW)、临床附着水平(CAL)和角化组织宽度(KTW)均得到了良好的改善。GUG 和 SCTG 组治疗后 6 个月的平均退缩缺陷覆盖百分比分别为 68.2±33%和 76.4±30.2%(p>0.05)。尽管在术后 6 个月时两组间在 RD、RW、CAL、RC、患者舒适度、美学满意度和过敏感度参数方面无统计学差异(p>0.05),但 GUG 组的 KTW 增加显著更高(p<0.05)。
虽然两种技术均有效,但对于 KTW 不足和(或)浅前庭深度的 RT1 牙龈退缩,GUG 是一种方便的治疗方法。
根据本研究结果,GUG 可能是角化组织缺乏的局限性牙龈退缩的首选治疗方法。临床试验注册号:NCT04637451。