Institut de Biologie de l'ENS (IBENS), Département de biologie, École normale supérieure, CNRS, INSERM, Université PSL, 75005 Paris, France.
CIRAD, UMR AGAP Institut, F-34398 Montpellier, France - UMR AGAP Institut, Univ Montpellier, CIRAD, INRAE, Institut Agro, F-34398 Montpellier, France.
Nucleic Acids Res. 2022 Jan 7;50(D1):D1025-D1031. doi: 10.1093/nar/gkab1091.
Genomicus is a database and web-server dedicated to comparative genomics in eukaryotes. Its main functionality is to graphically represent the conservation of genomic blocks between multiple genomes, locally around a specific gene of interest or genome-wide through karyotype comparisons. Since 2010 and its first release, Genomicus has synchronized with 60 Ensembl releases and seen the addition of functions that have expanded the type of analyses that users can perform. Today, five public instances of Genomicus are supporting a total number of 1029 extant genomes and 621 ancestral reconstructions from all eukaryotes kingdoms available in Ensembl and Ensembl Genomes databases complemented with four additional instances specific to taxonomic groups of interest. New visualization and query tools are described in this manuscript. Genomicus is freely available at http://www.genomicus.bio.ens.psl.eu/genomicus.
Genomicus 是一个数据库和网络服务器，专门用于真核生物的比较基因组学。它的主要功能是图形化地表示多个基因组之间基因组块的保守性，局部围绕感兴趣的特定基因，或通过染色体组比较进行全基因组范围的比较。自 2010 年首次发布以来，Genomicus 已经与 60 个 Ensembl 版本同步，并且增加了一些功能，扩展了用户可以执行的分析类型。如今，有五个公共实例的 Genomicus 支持来自 Ensembl 和 Ensembl 基因组数据库中的所有真核生物王国的 1029 个现存基因组和 621 个祖先重建，此外还有四个特定于感兴趣的分类群的额外实例。本文描述了新的可视化和查询工具。Genomicus 可免费在 http://www.genomicus.bio.ens.psl.eu/genomicus 获得。
