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[诺氟沙星在泌尿道病原菌比较中的体外比较活性]

[In vitro comparative activity of norfloxacin in the comparison of pathogenic bacteria of the urinary tract].

作者信息

Carlone N A, Cuffini A M, Tullio V, Savoia D, Cavallo G P

机构信息

Istituto di Microbiologia, Università di Torino.

出版信息

G Batteriol Virol Immunol. 1986 Jan-Jun;79(1-6):85-97.

PMID:3479370
Abstract

In this study 411 bacterial isolates from clinical urinary tract infections against some quinolones, azthreonam and trimethoprim + sulfamethoxazole combination were tested. Bactericidal kinetics of norfloxacin , cinoxacin and azthreonam against E. coli ATCC 25922 was determined. Both MICs values and bactericidal activities have shown that fluoroquinolones are more active against all Gram-positive and Gram-negative bacteria tested than the other drugs.

摘要

在本研究中,对411株从临床尿路感染分离出的细菌进行了针对某些喹诺酮类、氨曲南以及甲氧苄啶+磺胺甲恶唑组合药物的测试。测定了诺氟沙星、西诺沙星和氨曲南对大肠杆菌ATCC 25922的杀菌动力学。最低抑菌浓度(MIC)值和杀菌活性均表明,氟喹诺酮类药物对所有测试的革兰氏阳性菌和革兰氏阴性菌的活性均高于其他药物。

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