一杯香浓的觉醒：咖啡因对老年人的神经精神影响。

A Brewed Awakening: Neuropsychiatric Effects of Caffeine in Older Adults.

机构信息

Department of Psychiatry & Behavioral Neuroscience, Saint Louis University School of Medicine, 1438 Grand Boulevard, Saint Louis, MO 63104, USA.

出版信息

Clin Geriatr Med. 2022 Feb;38(1):133-144. doi: 10.1016/j.cger.2021.07.009.

DOI:10.1016/j.cger.2021.07.009

PMID:34794697

Abstract

This article provides a current review of the literature examining caffeine use in older adults. Caffeine use is prevalent among older adults; thus, providers need to be aware of the prevalence and diagnostic criteria of caffeine use disorder versus nonproblematic use. The relationship between caffeine and various neuropsychiatric disorders, including Parkinson's disease, Alzheimer's disease, insomnia, and late-life depression, is reviewed. The neurobiological effects of caffeine are described, along with clinically relevant interactions between caffeine and common psychotropic medications.

摘要

本文对研究老年人咖啡因使用情况的文献进行了综述。老年人中咖啡因的使用较为普遍；因此，医务人员需要了解咖啡因使用障碍与非问题性使用的流行情况和诊断标准。本文还回顾了咖啡因与各种神经精神障碍的关系，包括帕金森病、阿尔茨海默病、失眠和老年期抑郁症。本文还描述了咖啡因的神经生物学效应，以及咖啡因与常见精神药物之间的临床相关相互作用。