Almasaud Jluwi, Aledaili Sara A, Alshammari Reem S
Ophthalmology, King Khaled Hospital, Hail, SAU.
Medicine, University of Hail College of Medicine, Hail, SAU.
Cureus. 2021 Nov 13;13(11):e19521. doi: 10.7759/cureus.19521. eCollection 2021 Nov.
Ocular coloboma (OC) is a rare congenital anomaly and a product of a defect in embryogenesis. It is the result of fetal fissure closure error that ends with a persistent cleft. Colobomas are generally accompanied by visual loss. In this article, we present a case of bilateral iris, disc, and retina coloboma that was managed with an anti-vascular endothelial growth factor (ranibizumab), and as a result, caused regression of the choroidal neovascular membranes and improved the patient's visual acuity. However, The patient will need lifelong follow-up to catch any retinochoroidal changes or development of cataract or glaucoma.
眼裂缺(OC)是一种罕见的先天性异常,是胚胎发育缺陷的产物。它是胎儿裂闭合错误导致持续性裂隙的结果。裂缺通常伴有视力丧失。在本文中,我们报告了一例双侧虹膜、视盘和视网膜裂缺病例,该病例采用抗血管内皮生长因子(雷珠单抗)治疗,结果脉络膜新生血管膜消退,患者视力提高。然而,该患者需要终身随访,以发现任何视网膜脉络膜变化或白内障或青光眼的发展。