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儿童创伤与精神病:简要更新综述与病例研究。

Childhood Trauma and Psychosis: A Brief Updated Review and Case Study.

机构信息

Department of Psychiatry, University of Massachusetts Chan Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

出版信息

Child Adolesc Psychiatr Clin N Am. 2022 Jan;31(1):91-98. doi: 10.1016/j.chc.2021.08.002.

DOI:10.1016/j.chc.2021.08.002
PMID:34801157
Abstract

Significant evidence suggests strong links between childhood trauma and psychosis, with childhood trauma considered a significant risk factor for psychosis, causing a more severe presentation of psychotic illness with a dose-response effect. The relationship between anxiety, mood, posttraumatic stress disorder, and childhood trauma and psychosis and the difficulties distinguishing between overlapping symptoms require careful attention of the treating clinician considering the presentation and treatment course. Finally, there also appears to be a link between childhood trauma and violent behavior in individuals with psychotic illness. More research is needed into the effectiveness and safety of trauma-focused psychotherapeutic interventions.

摘要

大量证据表明,儿童时期创伤与精神病之间存在紧密联系,儿童时期创伤被认为是精神病的一个重要风险因素,会导致精神病的表现更为严重,并呈现出剂量反应效应。焦虑、情绪、创伤后应激障碍与儿童时期创伤和精神病之间的关系,以及区分重叠症状的困难,都需要治疗临床医生的密切关注,特别是在考虑到患者的表现和治疗过程时。最后,精神病患者的儿童时期创伤与暴力行为之间似乎也存在关联。需要进一步研究以确定以创伤为重点的心理治疗干预措施的有效性和安全性。

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1
Childhood Trauma and Psychosis: A Brief Updated Review and Case Study.儿童创伤与精神病:简要更新综述与病例研究。
Child Adolesc Psychiatr Clin N Am. 2022 Jan;31(1):91-98. doi: 10.1016/j.chc.2021.08.002.
2
[Post-traumatic stress disorder in reaction to psychotic experience: A systematic revue].[对精神病性体验的反应性创伤后应激障碍:一项系统综述]
Encephale. 2019 Dec;45(6):506-512. doi: 10.1016/j.encep.2019.07.006. Epub 2019 Sep 11.
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Childhood Trauma and Psychosis: An Updated Review.儿童期创伤与精神病:最新综述。
Child Adolesc Psychiatr Clin N Am. 2020 Jan;29(1):115-129. doi: 10.1016/j.chc.2019.08.004. Epub 2019 Sep 23.
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Distress, Psychotic Symptom Exacerbation, and Relief in Reaction to Talking about Trauma in the Context of Beneficial Trauma Therapy: Perspectives from Young People with Post-Traumatic Stress Disorder and First Episode Psychosis.在有益的创伤治疗背景下,谈论创伤时的痛苦、精神病症状加剧及缓解:创伤后应激障碍和首发精神病青年的观点
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Childhood trauma increases the risk of post-traumatic stress disorder in response to first-episode psychosis.儿童期创伤会增加首发精神病后创伤后应激障碍的风险。
Aust N Z J Psychiatry. 2012 Jan;46(1):35-9. doi: 10.1177/0004867411430877.
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Posttraumatic stress disorder with secondary psychotic features (PTSD-SP): Diagnostic and treatment challenges.创伤后应激障碍伴精神病性特征(PTSD-SP):诊断和治疗挑战。
Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jan 10;88:265-275. doi: 10.1016/j.pnpbp.2018.08.001. Epub 2018 Aug 6.
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[Psychosis and trauma. Theorical links between post-traumatic and psychotic symptoms].[精神病与创伤。创伤后症状与精神病症状之间的理论联系]
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Childhood trauma and posttraumatic stress disorder in patients with psychosis: clinical challenges and emerging treatments.儿童期创伤和精神病患者的创伤后应激障碍:临床挑战和新兴治疗方法。
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[Posttraumatic stress disorder (PTSD) as a consequence of the interaction between an individual genetic susceptibility, a traumatogenic event and a social context].[创伤后应激障碍(PTSD)作为个体遗传易感性、创伤性事件和社会环境之间相互作用的结果]
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A comparison of PTSD and traumatic event rates in a clinical sample of non-refugee immigrants and native-born individuals with a psychotic disorder: a case-control study.一项针对精神障碍临床样本中非难民移民和本土出生个体的 PTSD 和创伤性事件发生率的比较:病例对照研究。
Eur J Psychotraumatol. 2023;14(2):2263151. doi: 10.1080/20008066.2023.2263151. Epub 2023 Oct 17.

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The mediating role of neuroticism and anxiety sensitivity in the relationship between childhood trauma and panic disorder severity.神经质和焦虑敏感性在童年创伤与惊恐障碍严重程度关系中的中介作用。
Front Psychiatry. 2024 Oct 14;15:1441664. doi: 10.3389/fpsyt.2024.1441664. eCollection 2024.
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Association of childhood trauma with cognitive domains in adult patients with mental disorders and in non-clinical populations: a systematic review.成年精神障碍患者及非临床人群中儿童期创伤与认知领域的关联:一项系统综述
Front Psychol. 2023 Jun 23;14:1156415. doi: 10.3389/fpsyg.2023.1156415. eCollection 2023.