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可扩张与静态经椎间孔腰椎体间融合器:1 年的影像学参数和患者报告的结果。

Expandable versus Static Transforaminal Lumbar Interbody Fusion Cages: 1-year Radiographic Parameters and Patient-Reported Outcomes.

机构信息

Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois, USA.

Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

World Neurosurg. 2022 Mar;159:e1-e7. doi: 10.1016/j.wneu.2021.11.056. Epub 2021 Nov 18.

Abstract

OBJECTIVE

Expandable transforaminal lumbar interbody fusion (TLIF) cages capable of multidirectional in situ expansion have gained popularity as they increase axial surface area for fusion and may enhance lordotic correction through a traditional minimally invasive surgery (MIS) surgical corridor. We evaluated and compared the radiographic and clinical outcomes between a novel expandable versus static minimally invasive surgery TLIF cage for the treatment of degenerative disk disease.

METHODS

A single-center retrospective review of 120 consecutive adult patients undergoing 1- or 2-level MIS TLIF with an expandable (n = 60) or static cage was performed between 2015 and 2019. Preoperative and 1-year postoperative radiographic and clinical outcomes were assessed by upright flexion/extension radiographs and serial confidential surveys.

RESULTS

One-hundred twenty patients (mean age 63.5 years, 60.0% female) undergoing 1- and 2-level MIS TLIF met inclusion criteria. A statistically significant reduction of spondylolisthesis, restoration of foraminal height as well as anterior and posterior disk height was achieved in both cohorts, however was greater in the expandable cage cohort (ECC) (all P < 0.05). Comparable rates of fusion, 93% and 91%, were observed in the ECC and static cage cohort. A significant reduction in Numeric Pain Rating Scale back and Oswestry Disability Index scores were observed in both cohorts but were more pronounced in the ECC (5.9 ± 2.4 to 2.2 ± 1.9 and 37.3 ± 16.2 to 17.1 ± 15.2) versus static cage cohort (6.2 ± 2.8 to 3.2 ± 2.5 and 41.8 ± 16.1 to 24.3 ± 17.5) (P < 0.05). One instance of cage migration requiring reoperation occurred in the ECC.

CONCLUSIONS

Taken together, these radiographic and clinical findings suggest an expandable cage placed through an MIS corridor represents a safe, equitable, and efficacious alternative to a static TLIF in adults with degenerative lumbar pathology.

摘要

目的

可进行多向原位扩张的可扩张经椎间孔腰椎体间融合术(TLIF) cage 因其增加融合的轴向表面积并通过传统微创外科(MIS)手术通道可能增强脊柱前凸矫正而受到欢迎。我们评估和比较了新型可扩张与静态微创 TLIF cage 治疗退行性椎间盘疾病的放射学和临床结果。

方法

对 2015 年至 2019 年期间,在 1 个或 2 个水平进行微创 TLIF 的 120 例连续成年患者(可扩张组,n=60;静态 cage 组)进行了单中心回顾性研究。通过直立屈伸位 X 线片和连续的机密调查评估术前和 1 年时的放射学和临床结果。

结果

120 例患者(平均年龄 63.5 岁,60.0%女性)接受 1 级和 2 级微创 TLIF 符合纳入标准。在两组中,均显著降低了滑脱程度,恢复了椎间孔高度以及前、后椎间盘高度,但在可扩张 cage 组(ECC)中更为明显(均 P<0.05)。ECC 和静态 cage 组的融合率分别为 93%和 91%。两组的数字疼痛评分量表(Numeric Pain Rating Scale)背部和 Oswestry 残疾指数评分均显著降低,但在 ECC 组更为明显(5.9±2.4 至 2.2±1.9 和 37.3±16.2 至 17.1±15.2)与静态 cage 组(6.2±2.8 至 3.2±2.5 和 41.8±16.1 至 24.3±17.5)(均 P<0.05)。ECC 中有 1 例 cage 迁移需再次手术。

结论

综上所述,这些放射学和临床结果表明,在成人退行性腰椎病变患者中,通过 MIS 通道放置可扩张 cage 是一种安全、等效且有效的静态 TLIF 替代方法。

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