Akshayaa L, Lakshmi Thangavelu, Devaraj Ezhilarasan, Roy Anitha, Raghunandhakumar S, Sivaperumal P, David Sheba, Dua Kamal, Chellappan Dinesh Kumar
Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai-600077, TamilNadu.
PAPRSB Institute of Health Sciences, Universiti Brunei Darussalam, Brunei.
Bioinformation. 2020 Nov 30;16(11):878-881. doi: 10.6026/97320630016878. eCollection 2020.
Design and development of effective anti-virals in combating CoVid-19 is a great challenge worldwide. Known drugs such as chloroquine, lopinavir, favipiravir and remdesivir are used in the management of CoVid - 19. It is known that Ivermectin and remdesivir both are effective against filoviruses, paramyxo viruses. Available data also shows that ivermectin and remedesivir repress the replication of SARS-CoV-2. Thus, we document the potential use of ivermectin and remdesivir in the management of CoVid -19.
设计和开发有效的抗新冠病毒药物是全球面临的巨大挑战。氯喹、洛匹那韦、法匹拉韦和瑞德西韦等已知药物被用于新冠病毒的治疗。已知伊维菌素和瑞德西韦对丝状病毒、副粘病毒均有效。现有数据还表明,伊维菌素和瑞德西韦可抑制新冠病毒的复制。因此,我们记录了伊维菌素和瑞德西韦在新冠病毒治疗中的潜在用途。