He Calvin A, Smith Rory A, Wang Sharon, Arabian Sarkis, Hasan Mufadda
Pulmonary and Critical Care Medicine, Arrowhead Regional Medical Center, Colton, USA.
Infectious Disease, Arrowhead Regional Medical Center, Colton, USA.
Cureus. 2021 Oct 15;13(10):e18806. doi: 10.7759/cureus.18806. eCollection 2021 Oct.
tracheobronchitis (AT) is a rare manifestation of invasive aspergillosis. We present a case of tracheobronchitis caused by in a 33-year-old male with neutropenia and known human immunodeficiency virus (HIV) infection with acquired immunodeficiency syndrome (AIDS). A 33-year-old male with HIV/AIDS presented to the hospital with symptoms of productive cough for over two months associated with subjective fevers, chills, and body aches. Computed tomography (CT) of the chest was significant for scattered sub-centimeter bilateral upper lobe nodules but otherwise normal. The patient underwent an extensive evaluation for his respiratory symptoms, including an initial sputum culture, which grew in addition to preliminary fungal growth, prompting further evaluation with bronchoscopy. Bronchoscopy revealed diffuse adherent obstructive pseudomembranous plaques in the trachea and bilateral upper lobe segmental bronchi. Bronchoalveolar lavage cultures later grew . Tracheobronchitis due to species is a rare cause of infection in patients with HIV. We believe that this case underscores the importance of further evaluation utilizing bronchoscopy in patients with AIDS who have respiratory symptoms despite mild abnormalities on chest CT. This approach can be used to rule out atypical endobronchial infections such as tracheobronchitis due to species.
气管支气管炎(AT)是侵袭性曲霉病的一种罕见表现。我们报告一例由[具体病原体未给出]引起的气管支气管炎病例,患者为一名33岁男性,患有中性粒细胞减少症且已知感染人类免疫缺陷病毒(HIV)并患有获得性免疫缺陷综合征(AIDS)。一名患有HIV/AIDS的33岁男性因持续两个多月的咳痰症状就诊,伴有主观发热、寒战和全身疼痛。胸部计算机断层扫描(CT)显示双侧上叶散在的亚厘米级结节,但其他方面正常。患者针对其呼吸道症状接受了广泛评估,包括初始痰培养,除初步真菌生长外还培养出了[具体病原体未给出],这促使通过支气管镜进行进一步评估。支气管镜检查显示气管和双侧上叶段支气管有弥漫性附着的阻塞性假膜斑块。支气管肺泡灌洗培养后来培养出了[具体病原体未给出]。由[具体病原体未给出]引起的气管支气管炎是HIV患者感染的罕见原因。我们认为,该病例强调了对于胸部CT仅有轻度异常但有呼吸道症状的AIDS患者,利用支气管镜进行进一步评估的重要性。这种方法可用于排除非典型支气管内感染,如由[具体病原体未给出]引起的气管支气管炎。