Bazaid Abdulrahman S, Aldarhami Abdu, Gattan Hattan, Aljuhani Bakheet
Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hail, Hail, SAU.
Medical Microbiology, Qunfudah Faculty of Medicine, Umm Al-Qura University, Al-Qunfudah, SAU.
Cureus. 2021 Oct 19;13(10):e18882. doi: 10.7759/cureus.18882. eCollection 2021 Oct.
Treatment of wounds, especially chronic ones, is a major challenge in healthcare, with serious clinical and economic burdens. Multiple treatment approaches, including the usage of silver and iodine, have dramatically improved wound healing and reduced the incidence of infection. However, once infected by drug-resistant bacteria, treatment of wounds becomes a serious complication, with limited availability of effective antibiotic drugs, leading to high morbidity and mortality. Therefore, alternative therapeutic agents are required to address this gap in wound management. The introduction of manuka honey as a therapeutic agent against infected wounds was the result of extensive research about its activity against both planktonic and biofilm bacterial growth. Likewise, several types of Saudi honey (e.g., Sidr and Talh) showed promising in vitro and in vivo antimicrobial activity against wound pathogens. This short review summarizes literature that investigated the activity of common types of Saudi honey in relation to wound infections and explores their clinical utility.
伤口治疗，尤其是慢性伤口的治疗，是医疗保健领域的一项重大挑战，会带来严重的临床和经济负担。多种治疗方法，包括使用银和碘，已显著改善伤口愈合并降低感染发生率。然而，一旦伤口被耐药菌感染，治疗就会成为严重的并发症，有效抗生素药物供应有限，导致高发病率和高死亡率。因此，需要替代治疗剂来弥补伤口管理方面的这一空白。麦卢卡蜂蜜作为一种治疗感染伤口的治疗剂的引入，是对其针对浮游菌和生物膜细菌生长的活性进行广泛研究的结果。同样，几种沙特蜂蜜（如酸枣蜜和塔尔蜂蜜）对伤口病原体显示出有前景的体外和体内抗菌活性。这篇简短综述总结了研究沙特常见蜂蜜类型与伤口感染相关活性的文献，并探讨了它们的临床效用。
