Magalhães Edison S, Zimmerman Jeffrey J, Holtkamp Derald J, Classen Dyneah M, Groth Douglas D, Glowzenski Lauren, Philips Reid, Silva Gustavo S, Linhares Daniel C L
Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Carthage Veterinary Service, Ltd., Carthage, IL, United States.
Front Vet Sci. 2021 Nov 5;8:769312. doi: 10.3389/fvets.2021.769312. eCollection 2021.
Porcine reproductive and respiratory syndrome virus (PRRSV) became pandemic in the 1980's and today remains one of the most significant pathogens of the global swine industry. At the herd level, control of PRRSV is complicated by its extreme genetic diversity and its ability to persist in pigs, despite an active immune response. Ultimately, PRRSV control or elimination requires the coordination and active cooperation of producers and veterinarians at the regional level. Early voluntary PRRSV regional control programs focused on routine diagnostic testing and voluntary data-sharing regarding the PRRSV status of participants' herds, but no pre-defined action plans or decision trees were developed to secure project successes (or recover from failures). Given that control of PRRSV is paramount to producer profitability, we propose a coordinated approach for detecting, controlling, and ultimately eliminating wild-type PRRSV from herds participating in regional projects. Fundamental to project success is real-time, multi-platform communication of all data, information, and events that concern the regional project and project participants. New to this approach is the concept of agreed-upon action plans to be implemented by project participants in response to specific events or situations. The simultaneous and coordinated implementation of these strategies allows for early detection of wild-type PRRSV virus introductions and rapid intervention based on agreed-upon response plans. An example is given of a project in progress in the Midwest USA.
猪繁殖与呼吸综合征病毒(PRRSV)在20世纪80年代开始流行,至今仍是全球养猪业最重要的病原体之一。在猪群层面,PRRSV的控制因极度的基因多样性以及尽管存在活跃的免疫反应仍能在猪体内持续存在的能力而变得复杂。最终,PRRSV的控制或根除需要生产者和兽医在区域层面的协调与积极合作。早期的自愿性PRRSV区域控制项目侧重于常规诊断检测以及关于参与项目猪场PRRSV状况的自愿性数据共享,但并未制定预先确定的行动计划或决策树以确保项目成功(或从失败中恢复)。鉴于PRRSV的控制对生产者的盈利能力至关重要,我们提出一种协调方法,用于在参与区域项目的猪群中检测、控制并最终根除野生型PRRSV。项目成功的关键是实时、多平台地交流所有与区域项目及项目参与者相关的数据、信息和事件。这种方法的新颖之处在于商定的行动计划概念,项目参与者将根据特定事件或情况予以实施。这些策略的同步和协调实施能够早期检测到野生型PRRSV病毒的引入,并根据商定的应对计划进行快速干预。文中给出了美国中西部一个正在进行的项目的示例。