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2020 年加拿大艾伯塔省的甲型 H1N2 猪流感病毒变异株的特征描述。

Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020.

出版信息

Emerg Infect Dis. 2021;27(12):3045-3051. doi: 10.3201/eid2712.210298.

DOI:10.3201/eid2712.210298
PMID:34808085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8632177/
Abstract

Influenza strains circulating among swine populations can cause outbreaks in humans. In October 2020, we detected a variant influenza A subtype H1N2 of swine origin in a person in Alberta, Canada. We initiated a public health, veterinary, and laboratory investigation to identify the source of the infection and determine whether it had spread. We identified the probable source as a local pig farm where a household contact of the index patient worked. Phylogenetic analysis revealed that the isolate closely resembled strains found at that farm in 2017. Retrospective and prospective surveillance using molecular testing did not identify any secondary cases among 1,532 persons tested in the surrounding area. Quick collaboration between human and veterinary public health practitioners in this case enabled a rapid response to a potential outbreak.

摘要

猪群中流行的流感毒株可导致人类暴发疫情。2020 年 10 月,我们在加拿大艾伯塔省发现了一名患者感染了源自猪的甲型 H1N2 流感病毒变异株。我们启动了一项公共卫生、兽医和实验室调查,以确定感染源并确定其是否已传播。我们确定的可能来源是一家当地养猪场,该养猪场是该指数患者的一名家庭接触者工作的地方。系统进化分析显示,该分离株与 2017 年在该农场发现的菌株非常相似。使用分子检测进行回顾性和前瞻性监测,在周边地区检测的 1532 人中未发现任何继发病例。在该病例中,人类和兽医公共卫生从业者之间的快速协作使我们能够对潜在的疫情暴发做出快速反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/8632177/167f47723d64/21-0298-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/8632177/167f47723d64/21-0298-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/8632177/167f47723d64/21-0298-F.jpg

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