Bailey R R, Peddie B A
N Z Med J. 1985 Apr 24;98(777):286-8.
Enoxacin, a new orally absorbed broad spectrum anti-microbial agent, was used to treat 25 patients with moderate or severe urinary tract infections. Many were complicated and associated with renal insufficiency. Eighteen of the 25 were cured, five had a relapse and two became reinfected with a resistant Streptococcus faecalis. Fourteen of the patients reported side effects, including six with a neurological syndrome, one with widespread arthralgia and one with an Achilles tendonitis. Further studies are indicated with this potent drug to assess its role in the management of severe or complicated urinary infections and to assess the optimum dose and duration of therapy.
依诺沙星是一种新的口服吸收的广谱抗菌剂，用于治疗25例中度或重度尿路感染患者。许多病例病情复杂且伴有肾功能不全。25例患者中有18例治愈，5例复发，2例再次感染耐药粪肠球菌。14例患者报告有副作用，包括6例出现神经综合征，1例出现广泛关节痛，1例出现跟腱炎。需要对这种强效药物进行进一步研究，以评估其在严重或复杂性尿路感染治疗中的作用，并评估最佳治疗剂量和疗程。
