Liao Min-Tsun, Chen Chun-Kai, Lin Ting-Tse, Cheng Li-Ying, Ting Hung-Wen, Lai Chao-Lun
Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Hsinchu Branch, Hsinchu.
Institute of Epidemiology and Preventive Medicine, College of Public Health.
Acta Cardiol Sin. 2021 Nov;37(6):600-607. doi: 10.6515/ACS.202111_37(6).20210620A.
Atrial fibrillation is the most common arrhythmia and it is associated with a higher risk of mortality and morbidity. The goal of this study was to assess the correlation between physical activity (PA) and atrial high rate episodes (AHREs) detected by cardiovascular implantable electronic devices (CIEDs).
We prospectively collected data from 81 patients from March 2017 to June 2019. Device-detected PA (hours per day) through an accelerometer and occurrence/burden of AHREs were determined at each outpatient clinic visit. Modest AHREs and long AHREs were defined as at least 1 episode of AHREs lasting ≥ 12 hours and 24 hours, respectively. The percentage of total AHREs in the follow-up period was defined as the burden of AHREs. Generalized estimating equations were used to explore the association between PA and occurrence/burden of AHREs to account for repeated measures within a participant.
The patients had 336 follow-up visits (mean 4.1 visits each). The prevalence rates of device-detected modest AHREs and long AHREs were 4.8% and 3.9%, respectively. More PA (hours per day) was associated with a lower risk of modest AHREs [odds ratio (OR) 0.671, 95% confidence interval (CI) 0.452-0.997, p = 0.048] and long AHREs (OR 0.536, 95% CI 0.348-0.824, p = 0.004) after adjusting for age, sex, and basic characteristics. More PA had a trend of association with fewer AHREs (β -0.255, 95% CI -0.512 to 0.001, p = 0.051).
More PA was associated with a lower risk of AHREs detected by CIEDs in older patients. PA may reduce the risk of AHREs.
心房颤动是最常见的心律失常,与较高的死亡率和发病率相关。本研究的目的是评估体力活动(PA)与心血管植入式电子设备(CIED)检测到的心房高率发作(AHREs)之间的相关性。
我们前瞻性地收集了2017年3月至2019年6月期间81例患者的数据。在每次门诊就诊时,通过加速度计确定设备检测到的PA(每天小时数)以及AHREs的发生情况/负荷。适度AHREs和长时间AHREs分别定义为至少1次持续时间≥12小时和24小时的AHREs发作。随访期间总AHREs的百分比定义为AHREs的负荷。使用广义估计方程来探讨PA与AHREs的发生情况/负荷之间的关联,以考虑参与者内部的重复测量。
患者共进行了336次随访(平均每人4.1次)。设备检测到的适度AHREs和长时间AHREs的患病率分别为4.8%和3.9%。在调整年龄、性别和基本特征后,更多的PA(每天小时数)与适度AHREs风险降低相关[比值比(OR)0.671,95%置信区间(CI)0.452 - 0.997,p = 0.048],与长时间AHREs风险降低相关(OR 0.536,95% CI 0.348 - 0.824,p = 0.004)。更多的PA与较少的AHREs有相关趋势(β -0.255,95% CI -0.512至0.001,p = 0.051)。
在老年患者中,更多的PA与CIED检测到的AHREs风险降低相关。PA可能降低AHREs的风险。