Chen Chun-Kai, Cheng Li-Ying, Hsu Shan-Wei, Liao Min-Tsun, Ku Po-Wen, Liu Yen-Bin
Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
School of Nursing, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Front Cardiovasc Med. 2022 May 27;9:898086. doi: 10.3389/fcvm.2022.898086. eCollection 2022.
Physical activity (PA) has become an important health issue for decades. Cardiovascular implantable electronic devices (CIEDs) have built-in PA-recording functions. We aimed to compare PA measurements using an external accelerometer (ActiGraph GT3X+) and internal accelerometers (Abbott, Biotronik, and Medtronic CIEDs).
This was a prospective, single-center observational study. The device-measured 7-day average PA was collected, and GT3X+ -measured 7-day average PA was used as the gold-standard, including all daily observations of activity. Pearson's correlation coefficients were used to compare the correlations between GT3X+ -measured and CIED-measured PA. Bland-Altman plots were used to analyze measurement agreement, and intraclass correlation coefficients were used to analyze reliability.
In total, 720 patients treated with CIEDs were surveyed between November 2020 and April 2021, 60 of them were analyzed after patient screening by our protocol. Each manufacturer included 20 patients for the final analysis. The CIED-measured PAs of Abbott, Biotronik, and Medtronic were 3.0 ± 1.5, 2.6 ± 1.8, and 3.8 ± 2.5 h per day, respectively; the GT3X+ -measured PAs were 6.9 ± 2.8, 6.0 ± 2.4, and 6.4 ± 2.5 h per day, respectively. Moderate and significant correlations were found in patients using Abbott, Biotronik, and Medtronic CIEDs ( = 0.534, = 0.015; = 0.465, = 0.039; = 0.677, = 0.001, respectively). Bland-Altman plots and intraclass correlation coefficients both showed a significant correlation and reliability between the average PA measured by GT3X+ and CIEDs (hours per day).
Although the PA recording function of CIEDs includes a single-axis accelerometer, it has a moderate correlation compared with the triaxial accelerometer of the GT3X+. However, CIEDs seem to underestimate PA for 3-4 h compared to the GT3X+.
几十年来，身体活动（PA）已成为一个重要的健康问题。心血管植入式电子设备（CIED）具有内置的PA记录功能。我们旨在比较使用外部加速度计（ActiGraph GT3X+）和内部加速度计（雅培、百多力和美敦力CIED）测量PA的情况。
这是一项前瞻性、单中心观察性研究。收集设备测量的7天平均PA，将GT3X+测量的7天平均PA用作金标准，包括所有日常活动观察。使用Pearson相关系数比较GT3X+测量的PA与CIED测量的PA之间的相关性。使用Bland-Altman图分析测量一致性，使用组内相关系数分析可靠性。
2020年11月至2021年4月期间，共对720例接受CIED治疗的患者进行了调查，其中60例经我们的方案进行患者筛选后进行分析。每个制造商纳入20例患者进行最终分析。雅培、百多力和美敦力CIED测量的PA分别为每天3.0±1.5、2.6±1.8和3.8±2.5小时；GT3X+测量的PA分别为每天6.9±2.8、6.0±2.4和6.4±2.5小时。在使用雅培、百多力和美敦力CIED的患者中发现了中度和显著相关性（分别为r = 0.534，P = 0.015；r = 0.465，P = 0.039；r = 0.677，P = 0.001）。Bland-Altman图和组内相关系数均显示GT3X+测量的平均PA与CIED之间存在显著相关性和可靠性（每天小时数）。
尽管CIED的PA记录功能包括单轴加速度计，但与GT3X+的三轴加速度计相比，其相关性中等。然而，与GT3X+相比，CIED似乎低估了3 - 4小时的PA。
