Univ. Bordeaux, Inserm, BPH, UMR 1219, Bordeaux, France.
Nuffield Department of Population Health, University of Oxford, Big Data Institute, Oxford, United Kingdom.
Gerontology. 2022;68(7):755-762. doi: 10.1159/000518864. Epub 2021 Oct 18.
This study aimed to investigate whether self-rated health (SRH) predict frailty and its components among community dwellers aged 75 years and older.
We ran a cross-sectional and prospective analysis from 643 and 379 participants of the Bordeaux Center (France) of the Three-City Study, respectively. We assessed SRH using a single question with 5 response options. We defined frailty as having at least 3 out of the following 5 criteria: weight loss, exhaustion, slowness, weakness, and low energy expenditure. We used multivariate logistic regression and Cox proportional hazard models.
At baseline, poor SRH was significantly associated with frailty (odds ratio = 5.2; 95% confidence interval [CI]: 2.9-9.5) and its components except for weakness. In the prospective analysis on nonfrail participants, poor SRH was associated with the 4-year risk of slowness (hazard ratio [HR] = 1.7; 95% CI: 1.1-2.6) but not with that of frailty (HR = 1.6; 95% CI: 0.9-2.9) or the other components.
In a French cohort of community dwellers aged 75 years or older, poorer SRH was associated with concomitant frailty and 70% higher risk of slowness over 4 years.
本研究旨在探讨自评健康（SRH）是否可预测 75 岁及以上社区居民的虚弱及其组成部分。
我们分别对来自波尔多中心（法国）的三城研究的 643 名和 379 名参与者进行了横断面和前瞻性分析。我们使用 5 个选项的单一问题来评估 SRH。我们将虚弱定义为至少有以下 5 个标准中的 3 个：体重减轻、疲惫、缓慢、虚弱和低能量消耗。我们使用多变量逻辑回归和 Cox 比例风险模型。
在基线时，较差的 SRH 与虚弱（优势比=5.2；95%置信区间[CI]：2.9-9.5）及其组成部分显著相关，除了虚弱。在对非虚弱参与者的前瞻性分析中，较差的 SRH 与 4 年缓慢风险相关（风险比[HR]=1.7；95%CI：1.1-2.6），但与虚弱（HR=1.6；95%CI：0.9-2.9）或其他组成部分无关。
在法国 75 岁及以上社区居民的队列中，较差的 SRH 与同时存在的虚弱以及 4 年内缓慢风险增加 70%相关。
