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基于人群的波尔多三城队列研究中老年人群的自评健康与虚弱状况。

Self-Rated Health and Frailty in Older Adults from the Population-Based Three-City Bordeaux Cohort.

机构信息

Univ. Bordeaux, Inserm, BPH, UMR 1219, Bordeaux, France.

Nuffield Department of Population Health, University of Oxford, Big Data Institute, Oxford, United Kingdom.

出版信息

Gerontology. 2022;68(7):755-762. doi: 10.1159/000518864. Epub 2021 Oct 18.

Abstract

INTRODUCTION

This study aimed to investigate whether self-rated health (SRH) predict frailty and its components among community dwellers aged 75 years and older.

METHODS

We ran a cross-sectional and prospective analysis from 643 and 379 participants of the Bordeaux Center (France) of the Three-City Study, respectively. We assessed SRH using a single question with 5 response options. We defined frailty as having at least 3 out of the following 5 criteria: weight loss, exhaustion, slowness, weakness, and low energy expenditure. We used multivariate logistic regression and Cox proportional hazard models.

RESULTS

At baseline, poor SRH was significantly associated with frailty (odds ratio = 5.2; 95% confidence interval [CI]: 2.9-9.5) and its components except for weakness. In the prospective analysis on nonfrail participants, poor SRH was associated with the 4-year risk of slowness (hazard ratio [HR] = 1.7; 95% CI: 1.1-2.6) but not with that of frailty (HR = 1.6; 95% CI: 0.9-2.9) or the other components.

CONCLUSIONS

In a French cohort of community dwellers aged 75 years or older, poorer SRH was associated with concomitant frailty and 70% higher risk of slowness over 4 years.

摘要

简介

本研究旨在探讨自评健康(SRH)是否可预测 75 岁及以上社区居民的虚弱及其组成部分。

方法

我们分别对来自波尔多中心(法国)的三城研究的 643 名和 379 名参与者进行了横断面和前瞻性分析。我们使用 5 个选项的单一问题来评估 SRH。我们将虚弱定义为至少有以下 5 个标准中的 3 个:体重减轻、疲惫、缓慢、虚弱和低能量消耗。我们使用多变量逻辑回归和 Cox 比例风险模型。

结果

在基线时,较差的 SRH 与虚弱(优势比=5.2;95%置信区间[CI]:2.9-9.5)及其组成部分显著相关,除了虚弱。在对非虚弱参与者的前瞻性分析中,较差的 SRH 与 4 年缓慢风险相关(风险比[HR]=1.7;95%CI:1.1-2.6),但与虚弱(HR=1.6;95%CI:0.9-2.9)或其他组成部分无关。

结论

在法国 75 岁及以上社区居民的队列中,较差的 SRH 与同时存在的虚弱以及 4 年内缓慢风险增加 70%相关。

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