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乳制品摄入与法国老年社区居民虚弱长期风险的关系。

Dairy Product Intake and Long-Term Risk for Frailty among French Elderly Community Dwellers.

机构信息

Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos 36, Lebanon.

Institut National de la Santé et de la Recherche Médicale (INSERM), University Bordeaux, INSERM, BPH, U1219, F-33000 Bordeaux, France.

出版信息

Nutrients. 2021 Jun 23;13(7):2151. doi: 10.3390/nu13072151.

Abstract

Dairy products (DP) are part of a food group that may contribute to the prevention of physical frailty. We aimed to investigate DP exposure, including total DP, milk, fresh DP and cheese, and their cross-sectional and prospective associations with physical frailty in community-dwelling older adults. The cross-sectional analysis was carried out on 1490 participants from the Three-City Bordeaux cohort. The 10-year frailty risk was examined in 823 initially non-frail participants. A food frequency questionnaire was used to assess DP exposure. Physical frailty was defined as the presence of at least 3 out of 5 criteria of the frailty phenotype: weight loss, exhaustion, slowness, weakness, and low physical activity. Among others, diet quality and protein intake were considered as confounders. The baseline mean age of participants was 74.1 y and 61% were females. Frailty prevalence and incidence were 4.2% and 18.2%, respectively. No significant associations were observed between consumption of total DP or DP sub-types and frailty prevalence or incidence (OR = 1.40, 95%CI 0.65-3.01 and OR = 1.75, 95%CI 0.42-1.32, for a total DP consumption >4 times/d, respectively). Despite the absence of beneficial associations of higher DP consumption on frailty, older adults are encouraged to follow the national recommendations regarding DP.

摘要

乳制品(DP)是食物组的一部分,可能有助于预防身体虚弱。我们旨在研究 DP 的暴露情况,包括总 DP、牛奶、新鲜 DP 和奶酪,以及它们与社区居住的老年人身体虚弱的横断面和前瞻性关联。横断面分析在来自三城波尔多队列的 1490 名参与者中进行。在最初无虚弱的 823 名参与者中检查了 10 年的虚弱风险。使用食物频率问卷评估 DP 暴露情况。身体虚弱被定义为存在虚弱表型的至少 5 项标准中的 3 项:体重减轻、疲惫、缓慢、虚弱和低身体活动。除其他外,饮食质量和蛋白质摄入量被认为是混杂因素。参与者的基线平均年龄为 74.1 岁,61%为女性。虚弱的患病率和发病率分别为 4.2%和 18.2%。总 DP 或 DP 亚类的消耗与虚弱的患病率或发病率之间没有显著关联(总 DP 消耗 >4 次/天的 OR = 1.40,95%CI 0.65-3.01 和 OR = 1.75,95%CI 0.42-1.32)。尽管较高 DP 消耗对虚弱没有有益的关联,但鼓励老年人遵循 DP 的国家建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a03/8308304/e676ff51a0f7/nutrients-13-02151-g001.jpg

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