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纳米药物的商业效用与未来前景。

Commercial utilities and future perspective of nanomedicines.

作者信息

Malviya Rishabha, Fuloria Shivkanya, Verma Swati, Subramaniyan Vetriselvan, Sathasivam Kathiresan V, Kumarasamy Vinoth, Hari Kumar Darnal, Vellasamy Shalini, Meenakshi Dhanalekshmi Unnikrishnan, Yadav Shikha, Sharma Akanksha, Fuloria Neeraj Kumar

机构信息

Department of Pharmacy, SMAS, Galgotias University, Greater Noida, Uttar Pradesh, India.

Faculty of Pharmacy & Centre of Excellence for Biomaterials Engineering, AIMST University, Bedong, Kedah, Malaysia.

出版信息

PeerJ. 2021 Nov 19;9:e12392. doi: 10.7717/peerj.12392. eCollection 2021.

Abstract

The present review aims to describe the commercial utilities and future perspectives of nanomedicines. Nanomedicines are intended to increase precision medicine and decrease the adverse effects on the patient. Nanomedicines are produced, engineered, and industrialized at the cellular, chemical, and macromolecular levels. This study describes the various aspects of nanomedicine such as governing outlooks over high use of nanomedicine, regulatory advancements for nanomedicines, standards, and guidelines for nanomedicines as per Therapeutic Goods Administration (TGA). This review also focuses on the patents and clinical trials based on nanoformulation, along with nanomedicines utilization as drug therapy and their market value. The present study concludes that nanomedicines are of high importance in biomedical and pharmaceutical production and offer better therapeutic effects especially in the case of drugs that possess low aqueous solubility. The factual data presented in this study will assist the researchers and health care professionals in understanding the applications of nanomedicine for better diagnosis and effective treatment of a disease.

摘要

本综述旨在描述纳米药物的商业用途和未来前景。纳米药物旨在提高精准医疗水平并减少对患者的不良影响。纳米药物在细胞、化学和大分子水平上进行生产、设计和产业化。本研究描述了纳米药物的各个方面,例如对纳米药物高使用量的管理前景、纳米药物的监管进展、根据治疗用品管理局(TGA)制定的纳米药物标准和指南。本综述还关注基于纳米制剂的专利和临床试验,以及纳米药物作为药物治疗的应用及其市场价值。本研究得出结论,纳米药物在生物医学和制药生产中具有高度重要性,尤其在低水溶性药物的情况下能提供更好的治疗效果。本研究中呈现的实际数据将有助于研究人员和医疗保健专业人员了解纳米药物在疾病的更好诊断和有效治疗中的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1789/8607930/0433ae736d3b/peerj-09-12392-g001.jpg

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