Hohmann Stephan, Hillmann Henrike A K, Müller-Leisse Johanna, Eiringhaus Jörg, Zormpas Christos, Merten Roland, Veltmann Christian, Duncker David
Hannover Heart Rhythm Center, Department of Cardiology and Angiology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Department of Radiotherapy, Hannover Medical School, Hannover, Germany.
Herzschrittmacherther Elektrophysiol. 2022 Mar;33(1):49-54. doi: 10.1007/s00399-021-00830-y. Epub 2021 Nov 26.
Non-invasive stereotactic radioablation of ventricular tachycardia (VT) substrate has been proposed as a novel treatment modality for patients not eligible for catheter-based ablation or in whom this approach has failed. Initial clinical results are promising with good short-term efficacy in VT suppression and tolerable side effects. This article reviews the current clinical evidence for cardiac radioablation and gives an overview of important preclinical and translational results. Practical guidance is provided, and a cardiac radioablation planning and treatment workflow based on expert consensus and the authors' institutional experience is set out.
无创立体定向射频消融室性心动过速（VT）基质已被提议作为一种新的治疗方式，用于那些不适合基于导管的消融或该方法失败的患者。初步临床结果令人鼓舞，在抑制VT方面具有良好的短期疗效且副作用可耐受。本文回顾了心脏射频消融的当前临床证据，并概述了重要的临床前和转化研究结果。提供了实用指南，并阐述了基于专家共识和作者所在机构经验的心脏射频消融规划和治疗工作流程。
