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社区药剂师如何看待临床研究中的伦理:一项定性研究。

How Community Pharmacists Perceive Ethics in Clinical Research: A Qualitative Study.

作者信息

Ogura Miku, Takehira Rieko, Watanabe Tatsuya, Arita Etsuko

机构信息

Laboratory of Medical Psychology, Pharmaceutical Education Research Center, Kitasato University School of Pharmacy, Tokyo 108-8641, Japan.

Kitasato Clinical Research Center, Kitasato University School of Medicine, Sagamihara 252-0374, Japan.

出版信息

Healthcare (Basel). 2021 Nov 2;9(11):1496. doi: 10.3390/healthcare9111496.

Abstract

In recent years, the importance of building evidence in clinical practice that is increasingly acknowledged globally has been recognized in Japan as well, and it is expected that clinical research by community pharmacists will grow. In Japan, however, community pharmacists have few opportunities to learn about research ethics and may lack the training to make ethical decisions. We conducted a questionnaire survey of community pharmacists ( = 200) using a free descriptive format to understand how they perceived research ethics. Our qualitative analysis of 170 respondents revealed various perspectives (<A pharmacist's grounding>, , and ) of Japanese pharmacists on ethics in the context of clinical research. With respect to how to understand research, the following perspectives were found: "research that prioritizes researchers," "research that prioritizes research subjects (patients)," and "research that enters into regular work." The perspectives on "research that prioritizes research subjects (patients)" and "research that enters into regular work" may inadvertently lead to ethically inappropriate research due to mismatch in professional values or poor understanding of research. These findings can contribute to the development of an educational program for community pharmacists on research ethics.

摘要

近年来,在临床实践中积累证据的重要性在全球范围内日益得到认可,日本也不例外,预计社区药剂师开展的临床研究将会增加。然而,在日本,社区药剂师几乎没有机会学习研究伦理,可能也缺乏做出伦理决策的培训。我们对200名社区药剂师进行了问卷调查,采用自由描述格式,以了解他们对研究伦理的看法。我们对170名受访者的定性分析揭示了日本药剂师在临床研究背景下对伦理的各种观点(<药剂师的基础>、<药剂师对研究的看法>和<研究引发的伦理问题>)。关于如何理解研究,发现了以下观点:“以研究者为优先的研究”、“以研究对象(患者)为优先的研究”和“融入日常工作的研究”。由于专业价值观不匹配或对研究理解不足,“以研究对象(患者)为优先的研究”和“融入日常工作的研究”这两种观点可能会无意中导致不符合伦理的研究。这些发现有助于为社区药剂师制定研究伦理教育计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a3b/8623270/bdc98ed643a3/healthcare-09-01496-g001.jpg

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