Klentrou Panagiota, McKee Katherine, McKinlay Brandon J, Kurgan Nigel, Roy Brian D, Falk Bareket
Department of Kinesiology, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Centre for Bone and Muscle Health, Faculty of Applied Health Sciences, Brock University, St. Catharines, ON L2S 3A1, Canada.
Children (Basel). 2021 Oct 25;8(11):961. doi: 10.3390/children8110961.
Thirteen female adolescent soccer players (14.3 ± 1.3 years) participated in a cross-over, double-blind trial examining the effects of Greek yogurt (GY) consumption on bone biomarkers during 5 days of intense soccer training. The study took place over two intervention weeks, which consisted of a pre-training assessment day, 5 training days, and a post-training assessment day. Participants completed the GY condition and a carbohydrate isocaloric placebo control pudding condition (CHO) in random order, 4 weeks apart. Morning, fasted, resting blood samples were collected pre- and post-training in each condition. Total osteocalcin (tOC), undercarboxylated osteocalcin (unOC), C-terminal telopeptide of type 1 collagen (CTX), osteoprotegerin (OPG), and receptor activator nuclear factor kappa-β ligand (RANKL) were measured in serum. The results showed no effects for time (pre- to post-training) or condition, and no interaction for tOC, CTX, OPG, RANKL, and the OPG/RANKL ratio. A time-by-condition interaction ( = 0.011) was observed in unOC, reflecting a post-training decrease in the GY, but not the CHO condition (-26% vs. -3%, respectively). However, relative unOC (% of tOC) decreased post-training (-16%), with no differences between conditions. These findings suggest that short-term high-impact intense training had no direct catabolic impact on bone metabolism, with GY adding no benefit beyond that of the isocaloric CHO control pudding.
13名女性青少年足球运动员（14.3±1.3岁）参与了一项交叉双盲试验，该试验旨在研究在5天的高强度足球训练期间食用希腊酸奶（GY）对骨生物标志物的影响。该研究在两个干预周内进行，包括训练前评估日、5个训练日和训练后评估日。参与者以随机顺序完成GY组和等热量碳水化合物安慰剂对照布丁组（CHO），两组间隔4周。在每种情况下，训练前和训练后均采集空腹静息状态下的清晨血样。测定血清中的总骨钙素（tOC）、未羧化骨钙素（unOC）、I型胶原C端肽（CTX）、骨保护素（OPG）和核因子κ-β受体激活剂配体（RANKL）。结果显示，时间（训练前至训练后）或组别对tOC、CTX、OPG、RANKL及OPG/RANKL比值均无影响，也不存在交互作用。在unOC中观察到时间与组别之间的交互作用（P = 0.011），这反映出训练后GY组unOC降低，而CHO组未降低（分别为-26%和-3%）。然而，训练后相对unOC（占tOC的百分比）降低（-16%），两组之间无差异。这些研究结果表明，短期高强度的剧烈训练对骨代谢没有直接的分解代谢影响，与等热量的CHO对照布丁相比，GY并无额外益处。
