Ghitea Timea Claudia
Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410068 Oradea, Romania.
Biomedicines. 2021 Nov 18;9(11):1709. doi: 10.3390/biomedicines9111709.
Metabolic syndrome (MS) is correlated with many chronic diseases, and so far is moderately followed and treated. The present study follows a correlation of the presence of pathogens ( and others) in the gingival crevicular fluid and MS. (1) An important role in the fight against MS is to reduce fat mass, inflammatory mediators, and prevent cytokine-associated diseases. (2) A group of 111 people with MS was studied, divided into 3 groups. The control group (CG) received no treatment for either periodontitis or MS. The diet therapy group (DG) followed a clinical diet therapy specific to MS, and the diet therapy and sports group (DSG) in addition to diet therapy introduced regular physical activity; (3) A statistically significant worsening of periodontopathogens was observed correlated with the advancement of MS (increase in fat mass, visceral fat, and ECW/TBW ratio) in the CG group. In the case of DG and DSG groups, an improvement of the parameters was observed, including periodontal diseases. Therefore, anti-inflammatory diet therapy contributes to the reduction of gingival inflammation and thus contributes to the reduction of the development of pathogenic bacteria in the gingival, responsible for the development of periodontal disease and directly by other chronic diseases.
代谢综合征（MS）与许多慢性疾病相关，目前其受到的关注和治疗程度一般。本研究追踪了龈沟液中病原体（及其他因素）的存在与MS之间的相关性。（1）对抗MS的一个重要作用是减少脂肪量、炎症介质，并预防细胞因子相关疾病。（2）对111名患有MS的人进行了研究，将其分为3组。对照组（CG）未接受针对牙周炎或MS的治疗。饮食治疗组（DG）遵循针对MS的临床饮食疗法，饮食治疗和运动组（DSG）除饮食疗法外还引入了规律的体育活动；（3）在CG组中，观察到牙周病原体的统计学显著恶化与MS的进展（脂肪量、内脏脂肪和细胞外液/总体液比值增加）相关。在DG组和DSG组中，观察到各项参数有所改善，包括牙周疾病。因此，抗炎饮食疗法有助于减少牙龈炎症，从而有助于减少牙龈中致病细菌的滋生，这些细菌会导致牙周疾病，并直接引发其他慢性疾病。
