临床诊断为糖尿病患者牙周炎的患病率：一项流行病学研究的荟萃分析。
Prevalence of periodontitis in people clinically diagnosed with diabetes mellitus: a meta-analysis of epidemiologic studies.
机构信息
Department of Stomatology, School of Medicine, The First Affiliated Hospital, Shihezi University, Shihezi, Xinjiang, China.
Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
出版信息
Acta Diabetol. 2021 Oct;58(10):1307-1327. doi: 10.1007/s00592-021-01738-2. Epub 2021 May 24.
AIMS
The relationship between diabetes mellitus and periodontitis has long been discussed, but the conclusion of this relationship was controversial. We conducted this meta-analysis to explore the association between diabetes mellitus and the prevalence of periodontitis.
METHODS
PubMed, Embase, Web of Science, and the Cochrane Library were searched for studies reporting associations of periodontitis with diabetes. Gray literature was integrated from the Open-Gray database. Prevalence estimates and odds ratios were extracted by two independent reviewers and synthesized through meta-analyses.
RESULTS
Twenty-seven papers met the inclusion criteria involving 3092 diabetic patients and 23,494 controls. Overall prevalence of periodontitis was 67.8% in diabetics (combined types) and 35.5% in patients without diabetes (OR, 1.85; 95%CI, 1.61-2.11). Probing depth (MD 0.23; 95% CI, 0.17-0.29; I = 25%) and plaque index (MD, 0.20; 95% CI, 0.18-0.23; P = 0.59; I = 0%) severity scores were significantly greater among the diabetic group.
CONCLUSIONS
The prevalence and severity of periodontitis are greater in patients with diabetes than in non-diabetic populations.
目的
糖尿病与牙周炎之间的关系一直备受关注，但两者之间的关系尚无定论。我们进行了这项荟萃分析，旨在探讨糖尿病与牙周炎患病率之间的关联。
方法
检索 PubMed、Embase、Web of Science 和 Cochrane Library，以获取报告牙周炎与糖尿病相关性的研究。从 Open-Gray 数据库中整合灰色文献。两名独立评审员提取患病率估计值和优势比，并通过荟萃分析进行综合。
结果
27 篇文献符合纳入标准，涉及 3092 例糖尿病患者和 23494 例对照者。糖尿病患者（综合类型）的牙周炎总体患病率为 67.8%，而无糖尿病患者的患病率为 35.5%（OR，1.85；95%CI，1.61-2.11）。糖尿病组的探诊深度（MD 0.23；95%CI，0.17-0.29；I=25%）和菌斑指数（MD，0.20；95%CI，0.18-0.23；P=0.59；I=0%）严重程度评分显著更高。
结论
与非糖尿病人群相比，糖尿病患者的牙周炎患病率和严重程度更高。
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