Berghea Elena Camelia, Craiu Mihai, Ali Selda, Corcea Sabina Loredana, Bumbacea Roxana Silvia
Pediatrics Department, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Pediatrics, "Marie Curie" Emergency Children's Hospital, 077120 Bucharest, Romania.
Medicina (Kaunas). 2021 Nov 13;57(11):1240. doi: 10.3390/medicina57111240.
The most common clinical manifestation of mango allergy is contact dermatitis, which can be localized or systemic. The sensitising substances that have long been suspected are alk(en)yl catechols and/or alk(en)yl resorcinols.
We reviewed the original articles published on Pubmed, Embase and Cochrane Library before 15 September 2021, on the topic of contact allergy induced by mango and we synthesized the key data.
We found 12 case reports and four case series, with a total of 37 patients. Only seven of these cases were reported in patients from mango-cultivating countries, the other 30 were from countries where mango cultivation does not occur, and 26 were also from countries where poison ivy/oak are commonly found. We found that contact dermatitis may occur on the first exposure to mango due to previous sensitisation to urushiol-containing plants. The diagnosis was confirmed by patch testing in some of the cases. There was great heterogeneity between the reagents used.
Mango fruit is frequently consumed, but mango induced contact dermatitis, the main hypersensitivity reaction induced by mango, is rare. Further data is necessary for a better understanding of sensitising substances and, consecutively, standardization of patch test reagents.
芒果过敏最常见的临床表现是接触性皮炎，可局限或全身性发作。长期以来一直被怀疑的致敏物质是烷（烯）基儿茶酚和/或烷（烯）基间苯二酚。
我们检索了截至2021年9月15日在PubMed、Embase和Cochrane图书馆上发表的关于芒果引起的接触性过敏的原始文章，并综合了关键数据。
我们找到了12篇病例报告和4个病例系列，共37名患者。其中只有7例报告来自芒果种植国家的患者，其他30例来自不种植芒果的国家，还有26例来自常见毒葛/橡树的国家。我们发现，由于先前对含漆酚植物致敏，首次接触芒果时可能会发生接触性皮炎。部分病例通过斑贴试验确诊。所用试剂之间存在很大异质性。
芒果是常见的食用水果，但芒果引起的接触性皮炎，即芒果引起的主要超敏反应，却很罕见。需要更多数据来更好地了解致敏物质，并进而实现斑贴试验试剂的标准化。
