Department of Periodontics, Preventive and Restorative Dentistry, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany.
Department of Cardiology, University Heart and Vascular Center, 20246 Hamburg, Germany.
Nutrients. 2021 Nov 21;13(11):4167. doi: 10.3390/nu13114167.
The aim of the study was to investigate the relationship between specific known dietary patterns and the prevalence of periodontal disease in a northern population-based cohort study. We evaluated data from 6209 participants of the Hamburg City Health Study (HCHS). The HCHS is a prospective cohort study and is registered at ClinicalTrial.gov (NCT03934957). Dietary intake was assessed with the food frequency questionnaire (FFQ2). Periodontal examination included probing depth, gingival recession, plaque index, and bleeding on probing. Descriptive analyses were stratified by periodontitis severity. Ordinal logistic regression models were used to determine the association. Ordinal regression analyses revealed a significant association between higher adherence to the DASH diet/Mediterranean diet and lower odds to be affected by periodontal diseases in an unadjusted model (OR: 0.92; 95% CI: 0.87, 0.97; < 0.001/OR: 0.93; 95% CI: 0.91, 0.96; < 0.001) and an adjusted model (age, sex, diabetes) (OR: 0.94; 95% CI: 0.89, 1.00; < 0.0365/OR: 0.97; 95% CI: 0.94, 1.00; < 0.0359). The current cross-sectional study identified a significant association between higher adherence to the DASH and Mediterranean diets and lower odds to be affected by periodontal diseases (irrespective of disease severity). Future randomized controlled trials are needed to evaluate to which extent macro- and micronutrition can affect periodontitis initiation/progression.
本研究旨在调查特定已知饮食模式与北方人群为基础的队列研究中牙周病患病率之间的关系。我们评估了汉堡城市健康研究(HCHS)的 6209 名参与者的数据。HCHS 是一项前瞻性队列研究,已在 ClinicalTrials.gov 注册(NCT03934957)。饮食摄入通过食物频率问卷(FFQ2)进行评估。牙周检查包括探诊深度、牙龈退缩、菌斑指数和探诊出血。描述性分析按牙周炎严重程度分层。使用有序逻辑回归模型确定关联。有序回归分析显示,在未调整模型(OR:0.92;95%CI:0.87,0.97;<0.001/OR:0.93;95%CI:0.91,0.96;<0.001)和调整模型(年龄、性别、糖尿病)中,较高的 DASH 饮食/地中海饮食依从性与牙周病的患病几率较低呈显著相关(OR:0.94;95%CI:0.89,1.00;<0.0365/OR:0.97;95%CI:0.94,1.00;<0.0359)。本横断面研究确定了较高的 DASH 和地中海饮食依从性与牙周病患病几率较低之间存在显著相关性(无论疾病严重程度如何)。需要进一步开展随机对照试验,以评估宏观和微量营养素在多大程度上可以影响牙周炎的发生/进展。