Department of Animals and Poultry Science, College of Aburaihan, University of Tehran, Tehran, Iran.
Department of Animal Science, University of California, 2251 Meyer Hall, Davis, CA, 95616, USA.
Biol Trace Elem Res. 2022 Nov;200(11):4664-4677. doi: 10.1007/s12011-021-03045-x. Epub 2021 Nov 27.
The COVID-19 pandemic, which causes severe respiratory tract infections in humans, has become a global health concern and is spreading rapidly. At present, the most important issue associated with COVID-19 is the immune system and the factors that affect it. It is well known that cow's milk is highly rich in micronutrients that increase and strengthen the immune system. Research shows that the administration of these nutrients is very effective in fighting COVID-19, and a deficiency in any of them can be a weakness in the fight against the virus. On the other hand, cow's milk is accessible to the whole population, and drinking colostrum, raw, and micro-filtered milk from cows vaccinated against SARS-CoV-2 could provide individuals with short-term protection against the SARS-CoV-2 infection until vaccines become commercially available. This review aimed to discuss the effects of milk vitamins, minerals, and bioactive peptides on general health in humans to combat viral diseases, especially COVID-19, and to what extent cow's milk consumption plays a role in providing these metabolites. Cow's milk contains many bioactive compounds that include vitamins, minerals, biogenic amines, nucleotides, oligosaccharides, organic acids, and immunoglobulins. Humans can meet a significant portion of their requirements for vitamins and minerals through the consumption of cow's milk. Recent studies have shown that micronutrients such as vitamins D, E, B, C, and A as well as minerals Zn, Cu, Mg, I, and Se and bioactive peptides, each can have positive and significant effects on strengthening the immune system and general health in humans.
新型冠状病毒肺炎(COVID-19)是一种人类严重的呼吸道传染病,已成为全球关注的健康问题,并迅速传播。目前,与 COVID-19 相关的最重要问题是免疫系统及其影响因素。众所周知,牛奶富含能增强和加强免疫系统的微量营养素。研究表明,这些营养素的管理对对抗 COVID-19 非常有效,任何一种营养素的缺乏都可能成为对抗病毒的弱点。另一方面,牛奶是全民可获得的,饮用牛初乳、生乳和经 SARS-CoV-2 疫苗免疫的牛的微滤乳,可在疫苗上市之前为个体提供针对 SARS-CoV-2 感染的短期保护。本综述旨在讨论牛奶中的维生素、矿物质和生物活性肽对人类一般健康对抗病毒疾病(特别是 COVID-19)的影响,以及牛奶消费在提供这些代谢物方面的作用程度。牛奶含有许多生物活性化合物,包括维生素、矿物质、生物胺、核苷酸、低聚糖、有机酸和免疫球蛋白。人类可以通过饮用牛奶来满足对维生素和矿物质的大部分需求。最近的研究表明,维生素 D、E、B、C 和 A 以及矿物质 Zn、Cu、Mg、I 和 Se 以及生物活性肽等微量营养素,每一种都可以对增强人类的免疫系统和整体健康产生积极和显著的影响。