血清电解质和微量元素在 COVID-19 病理生理学中的作用综述
A Review on the Serum Electrolytes and Trace Elements Role in the Pathophysiology of COVID-19.
机构信息
Department of Medical Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran.
出版信息
Biol Trace Elem Res. 2021 Jul;199(7):2475-2481. doi: 10.1007/s12011-020-02377-4. Epub 2020 Sep 8.
Abstract
All the world is involved in the COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus is a positive-sense RNA and has an envelope. There is no specific drug for this disease and treatment methods are limited. Malnutrition and electrolyte imbalance can make dysfunction in the immune system and impairment of the immune system causes increasing the risk of infection. Understanding the aspects of biological features of the virus will help the development of diagnostic tests, pharmacological therapies, and vaccines. Here, we review and discuss increasing and decreasing some trace elements and imbalance of serum and plasma electrolytes involving in COVID-19.
摘要
全世界都受到了由严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2) 引起的 COVID-19 疾病的影响。冠状病毒是一种正链 RNA 病毒，具有包膜。目前尚无针对这种疾病的特效药，治疗方法有限。营养不良和电解质失衡会导致免疫系统功能障碍，而免疫系统受损会增加感染的风险。了解病毒的生物学特征有助于开发诊断检测、药物治疗和疫苗。在这里，我们回顾和讨论了 COVID-19 中涉及的一些微量元素的增加和减少以及血清和血浆电解质的失衡。
相似文献
1
A Review on the Serum Electrolytes and Trace Elements Role in the Pathophysiology of COVID-19.血清电解质和微量元素在 COVID-19 病理生理学中的作用综述
Biol Trace Elem Res. 2021 Jul;199(7):2475-2481. doi: 10.1007/s12011-020-02377-4. Epub 2020 Sep 8.
2
The British variant of the new coronavirus-19 (Sars-Cov-2) should not create a vaccine problem.新冠病毒-19（Sars-Cov-2）的英国变体不应造成疫苗问题。
J Biol Regul Homeost Agents. 2021 Jan-Feb;35(1):1-4. doi: 10.23812/21-3-E.
3
Trace element homeostasis in the neurological system after SARS-CoV-2 infection: Insight into potential biochemical mechanisms.新型冠状病毒感染后神经系统中的微量元素动态平衡：潜在生化机制的探讨。
J Trace Elem Med Biol. 2022 May;71:126964. doi: 10.1016/j.jtemb.2022.126964. Epub 2022 Feb 26.
4
Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA in Blood of Patients With Coronavirus Disease 2019 (COVID-19): What Does It Mean?2019冠状病毒病（COVID-19）患者血液中严重急性呼吸综合征冠状病毒2（SARS-CoV-2）RNA的检测：这意味着什么？
Clin Infect Dis. 2021 Nov 2;73(9):e2898-e2900. doi: 10.1093/cid/ciaa1316.
5
Obesity, malnutrition, and trace element deficiency in the coronavirus disease (COVID-19) pandemic: An overview.在冠状病毒病（COVID-19）大流行期间的肥胖、营养不良和微量元素缺乏：概述。
Nutrition. 2021 Jan;81:111016. doi: 10.1016/j.nut.2020.111016. Epub 2020 Sep 8.
6
Trace Element Zinc, a Nature's Gift to Fight Unprecedented Global Pandemic COVID-19.微量元素锌，大自然对抗史无前例的全球大流行病 COVID-19 的馈赠。
Biol Trace Elem Res. 2021 Sep;199(9):3213-3221. doi: 10.1007/s12011-020-02462-8. Epub 2020 Nov 10.
7
Comparison of trace element (selenium, iron), electrolyte (calcium, sodium), and physical activity levels in COVID-19 patients before and after the treatment.比较 COVID-19 患者治疗前后的微量元素（硒、铁）、电解质（钙、钠）和身体活动水平。
J Trace Elem Med Biol. 2022 Sep;73:127015. doi: 10.1016/j.jtemb.2022.127015. Epub 2022 May 30.
8
Leptin Deficiency, Caused by Malnutrition, Makes You Susceptible to SARS-CoV-2 Infection but Could Offer Protection from Severe COVID-19.由营养不良引起的瘦素缺乏会使你易感染新冠病毒，但可能为严重的新冠肺炎提供保护。
mSphere. 2021 May 12;6(3):e00031-21. doi: 10.1128/mSphere.00031-21.
9
Association of trace element status in COVID-19 patients with disease severity.新型冠状病毒肺炎患者微量元素状况与疾病严重程度的关系。
J Trace Elem Med Biol. 2022 Dec;74:127055. doi: 10.1016/j.jtemb.2022.127055. Epub 2022 Aug 4.
10
Electrolyte imbalances in patients with severe coronavirus disease 2019 (COVID-19).严重新型冠状病毒病（COVID-19）患者的电解质失衡。
Ann Clin Biochem. 2020 May;57(3):262-265. doi: 10.1177/0004563220922255. Epub 2020 May 3.
引用本文的文献
1
Assessment of Oxidative Stress Parameters in Iraqi Male Patients with Covid-19; A Case Control Study.伊拉克新冠肺炎男性患者氧化应激参数评估；一项病例对照研究。
Rep Biochem Mol Biol. 2024 Jul;13(2):167-173. doi: 10.61186/rbmb.13.2.167.
2
Real-time prognostic biomarkers for predicting in-hospital mortality and cardiac complications in COVID-19 patients.用于预测COVID-19患者院内死亡率和心脏并发症的实时预后生物标志物。
PLOS Glob Public Health. 2024 Mar 6;4(3):e0002836. doi: 10.1371/journal.pgph.0002836. eCollection 2024.
3
Association between biochemical and hematologic factors with COVID-19 using data mining methods.运用数据挖掘方法分析生物化学和血液学因素与 COVID-19 的关系。
BMC Infect Dis. 2023 Dec 21;23(1):897. doi: 10.1186/s12879-023-08676-0.
4
Use of data mining approaches to explore the association between type 2 diabetes mellitus with SARS-CoV-2.利用数据挖掘方法探索 2 型糖尿病与 SARS-CoV-2 之间的关联。
BMC Pulm Med. 2023 Jun 12;23(1):203. doi: 10.1186/s12890-023-02495-4.
5
Importance of Magnesium Status in COVID-19.镁状态在2019冠状病毒病中的重要性。
Biology (Basel). 2023 May 18;12(5):735. doi: 10.3390/biology12050735.
6
Content of Essential Trace Elements in the Hair of Residents of the Caspian Region of the Republic of Kazakhstan Who Recovered from COVID-19.从新冠病毒肺炎中康复的哈萨克斯坦共和国里海地区居民头发中必需微量元素的含量
Diagnostics (Basel). 2022 Nov 8;12(11):2734. doi: 10.3390/diagnostics12112734.
7
Association of serum zinc level and clinical outcome in Egyptian COVID-19 patients.埃及新冠肺炎患者血清锌水平与临床结局的关联
Egypt J Intern Med. 2022;34(1):72. doi: 10.1186/s43162-022-00159-z. Epub 2022 Sep 24.
8
A six-month study of anti-SARS-CoV-2 BNT162b2 mRNA vaccination: A comparative analysis of essential trace elements and anti-RBD IgG sera levels.一项针对抗 SARS-CoV-2 BNT162b2 mRNA 疫苗接种的六个月研究：必需微量元素和抗 RBD IgG 血清水平的比较分析。
J Trace Elem Med Biol. 2022 Dec;74:127079. doi: 10.1016/j.jtemb.2022.127079. Epub 2022 Sep 15.
9
Role of Matrix Degradation, Oxidative Stress, Inflammation & Trace Elements in COVID-19 Patients: A Multivariate Study from India.基质降解、氧化应激、炎症及微量元素在新冠肺炎患者中的作用：一项来自印度的多变量研究
Indian J Clin Biochem. 2023 Apr;38(2):193-203. doi: 10.1007/s12291-022-01059-3. Epub 2022 Sep 6.
10
Inflammatory-Metal Profile as a Hallmark for COVID-19 Severity During Pregnancy.炎症-金属谱作为孕期COVID-19严重程度的标志
Front Cell Dev Biol. 2022 Aug 9;10:935363. doi: 10.3389/fcell.2022.935363. eCollection 2022.
本文引用的文献
1
A Fourteen-day Experience with Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS): An Iranian Treatment Protocol.2019冠状病毒病（COVID-19）诱发急性呼吸窘迫综合征（ARDS）的14天治疗经验：一项伊朗治疗方案
Iran J Pharm Res. 2020 Winter;19(1):31-36. doi: 10.22037/ijpr.2020.113337.14239.
2
Can volcanic trace elements facilitate Covid-19 diffusion? A hypothesis stemming from the Mount Etna area, Sicily.火山微量元素会促进新冠病毒扩散吗？来自西西里岛埃特纳火山地区的假设。
Med Hypotheses. 2020 Nov;144:110058. doi: 10.1016/j.mehy.2020.110058. Epub 2020 Jun 27.
3
COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.新型冠状病毒肺炎与心血管疾病：从基础机制到临床展望。
Nat Rev Cardiol. 2020 Sep;17(9):543-558. doi: 10.1038/s41569-020-0413-9. Epub 2020 Jul 20.
4
COVID-19 Pandemic: Can Maintaining Optimal Zinc Balance Enhance Host Resistance?COVID-19 大流行：维持最佳锌平衡能否增强宿主抵抗力？
Tohoku J Exp Med. 2020 Jul;251(3):175-181. doi: 10.1620/tjem.251.175.
5
Iron metabolism and lymphocyte characterisation during Covid-19 infection in ICU patients: an observational cohort study.铁代谢和 ICU 患者 COVID-19 感染期间的淋巴细胞特征：一项观察性队列研究。
World J Emerg Surg. 2020 Jun 30;15(1):41. doi: 10.1186/s13017-020-00323-2.
6
Systemic hypoferremia and severity of hypoxemic respiratory failure in COVID-19.COVID-19患者的全身性低铁血症与低氧性呼吸衰竭的严重程度
Crit Care. 2020 Jun 9;24(1):320. doi: 10.1186/s13054-020-03051-w.
7
COVID-19: The Potential Role of Copper and N-acetylcysteine (NAC) in a Combination of Candidate Antiviral Treatments Against SARS-CoV-2.COVID-19：铜和 N-乙酰半胱氨酸（NAC）在联合使用候选抗病毒药物治疗 SARS-CoV-2 中的潜在作用。
In Vivo. 2020 Jun;34(3 Suppl):1567-1588. doi: 10.21873/invivo.11946.
8
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis.通过饮食和营养增强免疫系统、减轻炎症和氧化应激：COVID-19 危机期间的考虑因素。
Nutrients. 2020 May 27;12(6):1562. doi: 10.3390/nu12061562.
9
Can Zn Be a Critical Element in COVID-19 Treatment?锌能成为新冠肺炎治疗的关键元素吗？
Biol Trace Elem Res. 2021 Feb;199(2):550-558. doi: 10.1007/s12011-020-02194-9. Epub 2020 May 26.
10
Hyponatremia, IL-6, and SARS-CoV-2 (COVID-19) infection: may all fit together?低钠血症、白细胞介素-6与严重急性呼吸综合征冠状病毒2（COVID-19）感染：它们之间有关联吗？
J Endocrinol Invest. 2020 Aug;43(8):1137-1139. doi: 10.1007/s40618-020-01301-w. Epub 2020 May 25.
Zotero 插件