Key Laboratory of Biomechanics and Mechanobiology (Beihang University), Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing, People's Republic of China.
Orthopedics Department, Peking University International Hospital, Life Park 1, Zhongguancun Life Science Park, Changping District, Beijing, People's Republic of China.
Biomed Eng Online. 2021 Nov 27;20(1):119. doi: 10.1186/s12938-021-00956-7.
Long-leg-radiography (LLR) is commonly used for the measurement of lower limb alignment. However, limb rotations during radiography may interfere with the alignment measurement. This study examines the effect of limb rotation on the accuracy of measurements based on the mechanical and anatomical axes of the femur and tibia, with variations in knee flexion and coronal deformity.
Forty-five lower limbs of 30 patients were scanned with CT. Virtual LLRs simulating five rotational positions (neutral, ± 10[Formula: see text], and ± 20[Formula: see text] internal rotation) were generated from the CT images. Changes in the hip-knee-ankle angle (HKA) and the femorotibial angle (FTA) were measured on each image with respect to neutral values. These changes were related to knee flexion and coronal deformity under both weight- and non-weight-bearing conditions.
The measurement errors of the HKA and FTA derived from limb rotation were up to 4.84 ± 0.66[Formula: see text] and 7.35 ± 0.88[Formula: see text], respectively, and were correlated with knee flexion (p < 0.001) and severe coronal deformity (p < 0.001). Compared with the non-weight-bearing position, the coronal deformity measured in the weight-bearing condition was 2.62[Formula: see text] greater, the correlation coefficients between the coronal deformity and the deviation ranges of HKA and FTA were also greater.
Flexion and severe coronal deformity have a significant influence on the measurement error of lower limb alignment. Errors can be amplified in the weight-bearing condition compared with the non-weight-bearing condition. When using HKA and FTA to represent the mechanical axis and the anatomical axis on LLR, limb rotation impacts the anatomic axis more than the mechanical axis in patients with severe deformities. Considering LLR as the gold standard image modality, attention should be paid to the measurement of knee alignment. Especially for the possible errors derived from weight-bearing long-leg radiographs of patients with severe knee deformities.
长腿放射摄影(LLR)常用于下肢对线的测量。然而,在放射摄影过程中肢体的旋转可能会干扰对线的测量。本研究通过 CT 扫描检查了 30 名患者的 45 条下肢,研究了在膝关节屈伸和冠状面畸形的情况下,膝关节内、外翻 10°、20°时,股骨和胫骨机械轴和解剖轴的测量值的准确性。
从 CT 图像中生成模拟五个旋转位置(中立位、±10°、±20°内旋)的虚拟 LLR。在每种图像上,以中立位为参照,测量髋关节-膝关节-踝关节角(HKA)和股胫角(FTA)的变化。在承重和非承重条件下,将这些变化与膝关节屈伸和冠状面畸形相关联。
肢体旋转导致的 HKA 和 FTA 的测量误差最大可达 4.84±0.66°和 7.35±0.88°,与膝关节屈伸(p<0.001)和严重冠状面畸形(p<0.001)相关。与非承重位相比,承重位时冠状面畸形的测量值大 2.62°,HKA 和 FTA 偏差范围与冠状面畸形的相关系数也更大。
膝关节屈伸和严重冠状面畸形对线测量的误差有显著影响。承重位时的误差比非承重位时更大。在 LLR 上使用 HKA 和 FTA 代表机械轴和解剖轴时,对于严重畸形的患者,肢体旋转对线的解剖轴影响大于机械轴。考虑到 LLR 是金标准的影像学模式,应注意膝关节对线的测量。特别是对于严重膝关节畸形患者承重位长肢 X 线摄影可能产生的误差。