Gilbert Clément, Belliardo Carole
Université Paris-Saclay, CNRS, IRD, UMR Évolution, Génomes, Comportement et Écologie, Gif-sur-Yvette, 91198, France.
Université Côte d'Azur, INRAE, CNRS, Institut Sophia Agrobiotech, Sophia Antipolis, 06903, France; MYCOPHYTO, 540 Avenue de la Plaine, Mougins, 06250, France.
Curr Opin Insect Sci. 2022 Feb;49:48-55. doi: 10.1016/j.cois.2021.11.007. Epub 2021 Nov 26.
We provide an overview of the currently known diversity of viral sequences integrated into insect genomes. Such endogenous viral elements (EVE) have so far been annotated in at least eight insect orders and can be assigned to at least three families of large double-stranded (ds) DNA viruses, at least 22 families of RNA viruses, and three families of single-stranded DNA viruses. The study of these EVE has already produced important insights into insect-virus interactions, including the discovery of a new form of adaptive antiviral immunity. Insect EVE diversity will continue to increase as new insect genomes and exogenous viruses are sequenced, which will continue to make paleovirology a vibrant research field in this group of animals in the years to come.
我们概述了目前已知的整合到昆虫基因组中的病毒序列多样性。迄今为止，这种内源性病毒元件（EVE）已在至少八个昆虫目中得到注释，并可归为至少三个大型双链（ds）DNA病毒科、至少22个RNA病毒科和三个单链DNA病毒科。对这些EVE的研究已经为昆虫与病毒的相互作用提供了重要见解，包括发现了一种新的适应性抗病毒免疫形式。随着新的昆虫基因组和外源病毒被测序，昆虫EVE的多样性将继续增加，这将使古病毒学在未来几年内仍然是这类动物中的一个活跃的研究领域。
