Ultrasonography Department, Henan Province Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine), Zhengzhou, Henan Province 450002, China.
Special Inspection Department, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou Province 550001, China.
Comput Math Methods Med. 2021 Nov 18;2021:2577113. doi: 10.1155/2021/2577113. eCollection 2021.
In recent years, the incidence of thyroid cancer (TC) patients has gradually increased, and it ranks first among all endocrine tumors. TC has no obvious characteristics at the initial stage of onset. Thyroid tumors (TT) have formed when they are discovered, and they are easy to see when they are diagnosed. The disease is confused, so it is necessary to rely on imaging methods for tumor diagnosis. Contrast-enhanced ultrasound (CEUS), as the most commonly used imaging method in current clinical testing, is simple, safe, highly sensitive, can accurately display tumor conditions, and has high clinical value in the judgment of TC tumors. This article uses meta-analysis to select 63 published studies on CEUS to determine benign and malignant (BAM) TT to analyze and explore its clinical application value. This article understands the analysis of BAM TT and its diagnostic methods, clarifies the diagnostic efficiency of CEUS for TT, imaging methods, and imaging characteristics, and uses statistical analysis to analyze its heterogeneity. In this paper, the meta-analysis of CEUS in judging BAM TT is mainly based on references. The sensitivity, specificity, and difference of CEUS in diagnosing BAM TT are analyzed. Real-time elastography (RTE) is the comparison experiment object, and CEUS is used to compare the diagnostic efficiency, pathological results, and diagnostic efficiency of thyroid nodules in CEUS mode. The results of the study show that the nodule with higher diagnostic sensitivity is the echo feature, with a sensitivity of 97.73%, followed by the halo feature, with a sensitivity of 86.36%. In terms of diagnostic specificity, the boundary feature is the most specific. The specificity is 89.47%. In the judgment of BAM tumor nodules, the most obvious difference is the echo feature, which is as high as 14.09, followed by the acoustic halo feature, and the difference is 10.65.
近年来,甲状腺癌(TC)患者的发病率逐渐升高,在所有内分泌肿瘤中排名第一。TC 发病初期无明显特征,当发现甲状腺有肿瘤(TT)形成时,诊断时已经很明显。疾病的混淆,因此有必要依靠影像学方法进行肿瘤诊断。超声造影(CEUS)作为目前临床检测中最常用的影像学方法,简单、安全、灵敏度高,能准确显示肿瘤情况,在 TC 肿瘤的判断中具有很高的临床价值。本文采用荟萃分析,选取 63 篇关于 CEUS 的已发表研究,对良性和恶性(BAM)TT 进行判断分析,探讨其临床应用价值。本文了解了 BAM TT 的分析及其诊断方法,明确了 CEUS 对 TT 的诊断效率、成像方法和成像特征,并通过统计分析分析其异质性。本文主要基于参考文献对 CEUS 判断 BAM TT 的荟萃分析,分析 CEUS 诊断 BAM TT 的灵敏度、特异度和差异,以实时弹性成像(RTE)为对比实验对象,采用 CEUS 比较甲状腺结节在 CEUS 模式下的诊断效率、病理结果和诊断效率。研究结果表明,诊断敏感性较高的结节为回声特征,敏感性为 97.73%,其次为晕环特征,敏感性为 86.36%。在诊断特异性方面,边界特征最具特异性,特异性为 89.47%。在 BAM 肿瘤结节的判断中,最明显的差异是回声特征,高达 14.09,其次是声晕特征,差异为 10.65。