Koch Niharika, Islam Nazim F, Sonowal Songita, Prasad Ram, Sarma Hemen
Department of Botany, Mahatma Gandhi Central University, Motihari 845401, Bihar, India.
Department of Botany, Nanda Nath Saikia College, Titabar, Assam 785630, India.
Curr Res Microb Sci. 2021 Mar 14;2:100027. doi: 10.1016/j.crmicr.2021.100027. eCollection 2021 Dec.
In developing countries, the use of antibiotics has helped to reduce the mortality rate by minimizing the deaths caused by pathogenic infections, but the costs of antibiotic contamination remain a major concern. Antibiotics are released into the environment, creating a complicated environmental problem. Antibiotics are used in human, livestock and agriculture, contributing to its escalation in the environment. Environmental antibiotics pose a range of risks and have significant effects on human and animal health. Nevertheless, this is the result of the development of antibiotic-resistant and multi-drug-resistant bacteria. In the area of health care, animal husbandry and crop processing, the imprudent use of antibiotic drugs produces antibiotic-resistant bacteria. This threat is the deepest in the developing world, with an estimated 700,000 people suffering from antibiotic-resistant infections each year. The study explores how bacteria use a wide variety of antibiotic resistance mechanism and how these approaches have an impact on the environment and on our health. The paper focuses on the processes by which antibiotics degrade, the health effects of these emerging contaminants, and the tolerance of bacteria to antibiotics.
在发展中国家,抗生素的使用通过将致病性感染导致的死亡人数降至最低,有助于降低死亡率,但抗生素污染的成本仍然是一个主要问题。抗生素被释放到环境中,造成了复杂的环境问题。抗生素被用于人类、牲畜和农业领域,导致其在环境中的含量不断增加。环境中的抗生素带来了一系列风险,对人类和动物健康产生重大影响。然而,这是抗生素耐药菌和多重耐药菌发展的结果。在医疗保健、畜牧业和农作物加工领域,抗生素药物的不当使用产生了耐药菌。这种威胁在发展中世界最为严重,估计每年有70万人感染耐药菌。该研究探讨了细菌如何利用多种抗生素耐药机制,以及这些方式如何对环境和我们的健康产生影响。本文重点关注抗生素降解的过程、这些新兴污染物对健康的影响以及细菌对抗生素的耐受性。