麻醉医生尿液中致突变活性的检测：初步报告。
Detection of mutagenic activity in the urines of anesthesiologists: a preliminary report.
作者信息
McCoy E C, Hankel R, Rosenkranz H S, Giuffrida J G, Bizzari D V
出版信息
Environ Health Perspect. 1977 Dec;21:221-3. doi: 10.1289/ehp.7721221.
Abstract
While halothane was without mutagenic activity in the Salmonella mutagenicity assay, even in the presence of microsomal fractions, the urines of anesthesiologists induced mutations of the base-substitution type.
摘要
虽然氟烷在沙门氏菌致突变性试验中没有诱变活性，即使在存在微粒体组分的情况下也是如此，但麻醉医生的尿液却能诱导碱基置换型突变。
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本文引用的文献
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Editorial views: Anesthetics and cancer.社论观点：麻醉与癌症。
Anesthesiology. 1976 Jun;44(6):459-60. doi: 10.1097/00000542-197606000-00001.
3
Kinetics of methoxyflurane biotransformation with reference to substrate inhibition.
Anesthesiology. 1976 May;44(5):380-5. doi: 10.1097/00000542-197605000-00004.
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Metabolism of methoxyflurane in man.甲氧氟烷在人体中的代谢
Anesthesiology. 1976 May;44(5):372-9. doi: 10.1097/00000542-197605000-00003.
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Metabolism of (14C-1)-halothane in vivo--effects of multiple halothane anesthesia, phenobarbital and carbon tetrachloride pretreatment.
Biochem Pharmacol. 1975 Nov 15;24(22):2075-81. doi: 10.1016/0006-2952(75)90105-7.
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Anesthesiology. 1975 Oct;43(4):392-401. doi: 10.1097/00000542-197510000-00004.
7
Cancer and congenital anomalies associated with anesthetics.与麻醉相关的癌症和先天性异常。
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