宿主因素与疫苗效力：对 COVID-19 疫苗的启示。
Host factors and vaccine efficacy: Implications for COVID-19 vaccines.
机构信息
Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Department of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
出版信息
J Med Virol. 2022 Apr;94(4):1330-1335. doi: 10.1002/jmv.27485. Epub 2021 Dec 7.
Abstract
The efficacy of the vaccines varies between individuals and populations. The immunogenicity of the vaccine is influenced by various factors, including host factors. Previous studies have shown that host factors affect the effectiveness of vaccines, which may be true about COVID-19 vaccines. In this review, we evaluate the possible association of host factors with vaccine efficacy with a special focus on COVID-19 vaccines.
摘要
疫苗的效力在个体和人群之间有所差异。疫苗的免疫原性受多种因素影响，包括宿主因素。先前的研究表明，宿主因素会影响疫苗的有效性，这对于 COVID-19 疫苗来说可能也是如此。在这篇综述中，我们评估了宿主因素与疫苗效力的可能关联，特别关注 COVID-19 疫苗。
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