在水中以纳摩尔亲和力和大开启荧光对高极性酰胺 Squaraine 染料进行超分子捕获。
Supramolecular capture of highly polar amidosquaraine dye in water with nanomolar affinity and large turn-on fluorescence.
机构信息
Department of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA.
出版信息
Chem Commun (Camb). 2021 Dec 14;57(99):13518-13521. doi: 10.1039/d1cc05039g.
Abstract
A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and "turn on" visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage induced by the biomedically important enzyme phospholipase A.
摘要
一种包含阴离子型酰胺基方酸客和大环四元内酰胺主体的超分子染料捕获体系具有纳摩尔亲和力和“开启”可见荧光。该体系在一种新的荧光测定法中得到了应用，用于测定生物医学中重要的酶磷脂酶 A 诱导的脂质体泄漏。
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