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反刍思维介导童年期虐待和特质焦虑对非临床成年志愿者抑郁的影响。

Rumination Mediates the Effects of Childhood Maltreatment and Trait Anxiety on Depression in Non-Clinical Adult Volunteers.

作者信息

Deguchi Ayaka, Masuya Jiro, Naruse Mayu, Morishita Chihiro, Higashiyama Motoki, Tanabe Hajime, Inoue Takeshi, Ichiki Masahiko

机构信息

Department of Psychiatry, Tokyo Medical University, Shinjuku-ku, Tokyo, 160-0023, Japan.

Department of Psychiatry, Maruyamasou Hospital, Ishioka, Ibaraki, 315-0116, Japan.

出版信息

Neuropsychiatr Dis Treat. 2021 Nov 23;17:3439-3445. doi: 10.2147/NDT.S332603. eCollection 2021.

Abstract

BACKGROUND

Several psychological studies have shown that depressive rumination is associated with the onset and severity of depression. However, it is unclear how rumination interacts with other predisposing factors to cause depression. In this study, we hypothesized that rumination mediates the association between depression and two predisposing factors of depression, ie, childhood maltreatment and trait anxiety.

SUBJECTS AND METHODS

Between 2017 and 2018, 473 adult volunteers were surveyed using self-report questionnaires regarding the following: demographic information, rumination (Ruminative Responses Scale), trait anxiety (State-Trait Anxiety Inventory-Y), and the experience of childhood maltreatment (Child Abuse and Trauma Scale). The effects of these factors on depression (Patient Health Questionnaire-9) were analyzed by multiple regression and path analysis to analyze the mediating effects of rumination. This study was conducted with approval from the relevant ethics committee.

RESULTS

Multiple regression analysis using depression as a dependent variable demonstrated that trait anxiety, rumination, childhood maltreatment, and living alone were significantly associated with depression. Path analysis showed that childhood maltreatment had a positive effect on trait anxiety, rumination, and depression; trait anxiety had a positive effect on rumination and depression; and rumination had a positive effect on depression. Regarding indirect effects, the experience of childhood maltreatment increased rumination and depression indirectly via trait anxiety. Furthermore, the experience of childhood maltreatment increased depression indirectly via rumination, and trait anxiety significantly increased depression via rumination. In other words, rumination mediated the indirect effects of abusive experiences and trait anxiety on depression. This model accounted for 50% of the variance in depression in adult volunteers.

CONCLUSION

Our results suggest that rumination mediates the association between childhood maltreatment, trait anxiety, and depression in adulthood.

摘要

背景

多项心理学研究表明,抑郁性沉思与抑郁症的发作及严重程度相关。然而,尚不清楚沉思如何与其他诱发因素相互作用导致抑郁症。在本研究中,我们假设沉思介导了抑郁症与抑郁症的两个诱发因素之间的关联,即童年期虐待和特质焦虑。

对象与方法

在2017年至2018年期间,使用自我报告问卷对473名成年志愿者进行了调查,内容包括:人口统计学信息、沉思(沉思反应量表)、特质焦虑(状态-特质焦虑量表-青年版)以及童年期虐待经历(儿童虐待与创伤量表)。通过多元回归和路径分析来分析这些因素对抑郁症(患者健康问卷-9)的影响,以分析沉思的中介作用。本研究在相关伦理委员会批准下进行。

结果

以抑郁症为因变量的多元回归分析表明,特质焦虑、沉思、童年期虐待和独居与抑郁症显著相关。路径分析显示,童年期虐待对特质焦虑、沉思和抑郁症有正向影响;特质焦虑对沉思和抑郁症有正向影响;沉思对抑郁症有正向影响。关于间接效应,童年期虐待经历通过特质焦虑间接增加了沉思和抑郁症。此外,童年期虐待经历通过沉思间接增加了抑郁症,特质焦虑通过沉思显著增加了抑郁症。换句话说,沉思介导了虐待经历和特质焦虑对抑郁症的间接影响。该模型解释了成年志愿者抑郁症变异的50%。

结论

我们的结果表明,沉思介导了童年期虐待、特质焦虑与成年期抑郁症之间的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8d58/8627303/4f148707d0f1/NDT-17-3439-g0001.jpg

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