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接种基于灭活病毒的新冠疫苗后发生的颈段纵向广泛脊髓炎

Cervical longitudinally extensive myelitis after vaccination with inactivated virus-based COVID-19 vaccine.

作者信息

Sepahvand Mahsa, Yazdi Narges, Rohani Mohammad, Emamikhah Maziar

机构信息

Department of Neurology, Rasool Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Radiol Case Rep. 2022 Feb;17(2):303-305. doi: 10.1016/j.radcr.2021.10.053. Epub 2021 Nov 25.

Abstract

Myelitis, including longitudinally extensive transverse myelitis (LTEM), is reported in more than forty patients after coronavirus disease 2019 (COVID-19). Among COVID-19 vaccines, only Oxford-AstraZeneca COVID-19 vaccine (AZD1222) has been associated with few cases of myelitis (1 LTEM). We report the first case of myelitis/LTEM after BBIBP-CorV/Sinopharm vaccine, interestingly presented as a hemicord syndrome. A 71-year-old male presented with left-side diplegia, right-side hemihyposthesis with facial sparing and impaired position sensation in left foot after vaccination with BBIBP-CorV. MRI revealed a longitudinal signal in left cervical hemicord. This is the first reported myelitis and LTEM with COVID-19 vaccines other than AZD1222.

摘要

据报道,2019冠状病毒病(COVID-19)后有40多名患者发生了脊髓炎,包括长节段横贯性脊髓炎(LTEM)。在COVID-19疫苗中,只有牛津-阿斯利康COVID-19疫苗(AZD1222)与少数脊髓炎病例(1例LTEM)有关。我们报告了第一例接种BBIBP-CorV/国药疫苗后发生脊髓炎/LTEM的病例,有趣的是,该病例表现为半侧脊髓综合征。一名71岁男性在接种BBIBP-CorV后出现左侧双瘫、右侧半身感觉减退伴面部感觉保留以及左脚位置觉受损。MRI显示左侧颈髓半侧有纵向信号。这是除AZD1222之外,首次报道的与COVID-19疫苗相关的脊髓炎和LTEM病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/771d/8633815/e7c72b452a92/gr1.jpg

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