Beckstead J H
Arch Pathol Lab Med. 1986 Mar;110(3):175-9.
Recent technical advances have dramatically improved the diagnostic information available from a properly prepared bone marrow biopsy specimen. The most important of these is the ability to perform both enzyme histochemical and immunohistochemical procedures on the bone marrow biopsy specimen. These techniques make it possible to apply marker studies to all leukemias, including those with marrows that cannot be aspirated, and to focal lesions that may not be present in aspirated material. This review outlines the optimal use of the bone marrow biopsy as a tool in the evaluation of human bone marrow.
最近的技术进步极大地改善了从制备得当的骨髓活检标本中获得的诊断信息。其中最重要的是能够在骨髓活检标本上同时进行酶组织化学和免疫组织化学检测。这些技术使得对所有白血病进行标记研究成为可能，包括那些骨髓无法抽吸的白血病，以及可能不存在于抽吸物中的局灶性病变。这篇综述概述了骨髓活检作为评估人类骨髓的工具的最佳应用。
