Department of Orthopaedics, The Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Department of Hand-Foot Microsurgery, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China.
Comput Math Methods Med. 2021 Nov 23;2021:8294267. doi: 10.1155/2021/8294267. eCollection 2021.
In order to improve the repair effect after peripheral nerve injury, this paper analyzes the related influencing factors. The regeneration of peripheral nerve includes two continuous and overlapping processes: the acute wound healing period and the axon seeking target tissue period. The complete and effective process of peripheral nerve regeneration includes the sprouting, growth and extension of regenerated axons, and the reconstruction of synaptic connections (neuromuscular junctions) with target organs to realize the reinnervation of nerves and restore function. This process includes three indicators of success in regeneration: structural reconstruction, metabolic regeneration, and functional recovery. In order to improve the repair effect of peripheral nerve injury, relevant influencing factors can be analyzed, and effective improvement of these influencing factors can improve the recovery effect of peripheral nerve injury. Finally, this paper analyzes multiple factors to provide theoretical references for follow-up clinical diagnosis and treatment.
为了提高周围神经损伤后的修复效果，本文分析了相关影响因素。周围神经的再生包括两个连续且重叠的过程：急性伤口愈合期和轴突寻找靶组织期。周围神经再生的完整而有效的过程包括再生轴突的萌芽、生长和延伸，以及与靶器官的突触连接（运动终板）的重建，以实现神经的再支配并恢复功能。这个过程包括三个成功再生的指标：结构重建、代谢再生和功能恢复。为了提高周围神经损伤的修复效果，可以分析相关影响因素，有效改善这些影响因素可以提高周围神经损伤的恢复效果。最后，本文分析了多个因素，为后续临床诊断和治疗提供了理论参考。
