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从肠道炎症到骨骼关节:炎症性肠病(IBD)中的肌肉骨骼检查。

From bowel inflammation to the bone and joints: musculoskeletal examination in inflammatory bowel disease (IBD).

机构信息

Golestan Rheumatology Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Golestan Research Center of Gastroenterology and Hepatology, GolestanUniversity of Medical Sciences, 3rd floor, Heart Complex, Sayyad-e-Shirazi Hospital, Sayyad-e-Shirazi Boulevard, Gorgan city, Golestan province, Iran.

出版信息

BMC Musculoskelet Disord. 2021 Dec 4;22(1):1019. doi: 10.1186/s12891-021-04903-4.

Abstract

BACKGROUND

One of the most important complications in inflammatory Bowel Disease (IBD) are musculoskeletal manifestations that are reported in more than 50% of patients.

OBJECTIVES

In this study, we aimed to evaluate the musculoskeletal and radiologic manifestations in our IBD patients.

METHODS

In this cross-sectional study on 96 mild-to-moderate IBD patients (76 UC, 18 CD and 2 undifferentiated IBD) with mean (SD) age of 39.28 (11.42) years, 44 (45.8%) were males and 52 were (54.2%) females. Patients were examined by an expert rheumatologist and their musculoskeletal symptoms were assessed. The musculoskeletal system was evaluated by Modified Schober test, Thoracic expansion (TE), Occiput to wall distance (OWD), and Patrick's or FABER test. Peripheral joints were also examined in all four extremities. Then patients were referred for pelvic and lumbosacral x-ray. Sacroiliitis grading was performed using the New York criteria.

RESULTS

Inflammatory low back pain was reported in 5 (5.2%), enthesopathy in 6 (6.5%) and dactylitis in 1 (1.1%). Positive Schober test was recorded in 5 (5.2%) and Patrick test in 3 (3.1%). Forty-nine (51%) cases had normal imaging with no sacroiliitis, endplate sclerosis was seen in 33 cases (34.4%), grade 3 and grade 4 were seen in 10 cases (10.4%).

CONCLUSIONS

In the present study, 34.4% of the IBD patients had mild radiologic changes as endplate sclerosis and 95% had a normal physical examination.

摘要

背景

炎症性肠病(IBD)最重要的并发症之一是肌肉骨骼表现,超过 50%的患者会出现这种并发症。

目的

本研究旨在评估我们的 IBD 患者的肌肉骨骼和放射学表现。

方法

这是一项横断面研究,共纳入 96 例轻中度 IBD 患者(76 例 UC,18 例 CD 和 2 例未分化 IBD),平均(SD)年龄为 39.28(11.42)岁,其中 44 例(45.8%)为男性,52 例(54.2%)为女性。由一名专家风湿病学家对患者进行检查,并评估其肌肉骨骼症状。通过改良 Schober 试验、胸椎扩张(TE)、枕骨到墙的距离(OWD)和 Patrick 或 FABER 试验评估肌肉骨骼系统。还对所有四肢的外周关节进行了检查。然后将患者转介进行骨盆和腰骶部 X 线检查。根据纽约标准对骶髂关节炎进行分级。

结果

报告有 5 例(5.2%)出现炎症性下腰痛,6 例(6.5%)出现肌腱病,1 例(1.1%)出现指(趾)炎。5 例(5.2%)Schober 试验阳性,3 例(3.1%)Patrick 试验阳性。49 例(51%)患者影像学正常,无骶髂关节炎,33 例(34.4%)可见终板硬化,10 例(10.4%)可见 3 级和 4 级。

结论

在本研究中,34.4%的 IBD 患者有轻度放射学改变,表现为终板硬化,95%的患者体格检查正常。

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