Moser S A, Friedman L, Varraux A R
J Clin Microbiol. 1978 Mar;7(3):316-8. doi: 10.1128/jcm.7.3.316-318.1978.
Cryptococcus neoformans was isolated repeatedly from a patient with epider-moid carcinoma and pulmonary blastomycosis. The isolate was atypical in that it had only a minute capsule, caused persistent infection but no perceptible disease in mice, and initially appeared not to assimilate trehalose. Only after an incubation of 2 to 3 weeks did utilization of this substrate become apparent.
新型隐球菌多次从一名患有表皮样癌和肺芽生菌病的患者身上分离出来。该分离株具有非典型性,因为它只有微小的荚膜,能引起持续感染,但在小鼠中未引发明显疾病,并且最初似乎不能利用海藻糖。仅在培养2至3周后,对这种底物的利用才变得明显。