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脑脊液IgM指数与白塞病中枢神经系统受累的相关性

Association of cerebrospinal fluid IgM index with central nervous system involvement in Behçet's disease.

作者信息

Hirohata S, Takeuchi A, Miyamoto T

出版信息

Arthritis Rheum. 1986 Jun;29(6):793-6. doi: 10.1002/art.1780290614.

DOI:10.1002/art.1780290614
PMID:3487325
Abstract

Immunoglobulin (IgM, IgA, and IgG) and albumin values were determined in 12 patients who had signs and symptoms of central nervous system involvement attributable to Behçet's disease. Only the cerebrospinal fluid IgM index, which was significantly elevated in patients with active neuro-Behçet's syndrome, was found to decrease when the neurologic manifestations of the disease had disappeared. This indicates that determination of this index may be of help in the evaluation of central nervous system disease activity in neuro-Behçet's syndrome.

摘要

对12例有白塞病所致中枢神经系统受累体征和症状的患者测定了免疫球蛋白(IgM、IgA和IgG)及白蛋白值。仅发现脑脊液IgM指数在活动性神经白塞综合征患者中显著升高,而当疾病的神经学表现消失时该指数下降。这表明该指数的测定可能有助于评估神经白塞综合征中枢神经系统疾病的活动情况。

相似文献

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Association of cerebrospinal fluid IgM index with central nervous system involvement in Behçet's disease.脑脊液IgM指数与白塞病中枢神经系统受累的相关性
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引用本文的文献

1
Neuro-Behçet's disease: an update of clinical diagnosis, biomarkers, and immunopathogenesis.神经白塞病:临床诊断、生物标志物及免疫发病机制的最新进展
Clin Exp Immunol. 2025 Jan 21;219(1). doi: 10.1093/cei/uxae123.
2
CNS involvement in neuro-Behçet syndrome: an MR study.中枢神经系统受累于神经白塞病综合征:一项磁共振成像研究。
AJNR Am J Neuroradiol. 1999 Jun-Jul;20(6):1015-24.