Hubei Key Laboratory of Animal Embryo and Molecular Breeding, Institute of Animal Science and Veterinary Medicine, Hubei Academy of Agricultural Sciences, Wuhan, China.
State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China.
Anim Sci J. 2021 Jan-Dec;92(1):e13665. doi: 10.1111/asj.13665.
Magnolol is a multifunctional polyphenol rich in Magnolia officinalis. The objective of this study was to investigate the effects of magnolol on growth performance, carcass traits, antioxidant capacity, and gut health of broiler chickens. A total of 240 1-day-old broilers were randomly allocated into five dietary treatments: control (Ctrl); control diet supplemented with 100, 200, or 300 mg/kg of magnolol (M100, M200, and M300); and control diet supplemented with 200 mg/kg of bacitracin zinc (PC). The results showed that magnolol linearly decreased the feed conversion ratio between d 0 and d 14, linearly decreased the amount of malondialdehyde and increased the activity of total superoxide dismutase (T-SOD) in both serum and ileal mucosa on d 42 with increasing magnolol levels (p < 0.05). Moreover, the ileal villus height, the ileal villus height to crypt depth ratio, and the jejunal gene expressions of SOD1, glutathione peroxidase, and Claudin1 were linearly up-regulated with increasing magnolol levels (p < 0.05). The supplementation of magnolol had no effect on carcass traits or cecal short chain fatty acids (p > 0.05). The results indicated that magnolol could be applied in the diet of broiler chickens to benefit their antioxidant capacity and intestinal health.
厚朴酚是一种富含于厚朴的多功能多酚。本研究旨在探究厚朴酚对肉鸡生长性能、胴体特性、抗氧化能力和肠道健康的影响。将 240 只 1 日龄肉鸡随机分为 5 个日粮处理组：对照组（Ctrl）；对照组日粮中添加 100、200 或 300mg/kg 厚朴酚（M100、M200 和 M300）；对照组日粮中添加 200mg/kg 杆菌肽锌（PC）。结果表明，随着厚朴酚水平的提高，肉鸡在 0-14 日龄的饲料转化率呈线性降低，在 42 日龄时血清和回肠黏膜中的丙二醛含量呈线性降低，总超氧化物歧化酶（T-SOD）活性呈线性升高（p<0.05）。此外，随着厚朴酚水平的提高，回肠绒毛高度、绒毛高度与隐窝深度比以及空肠 SOD1、谷胱甘肽过氧化物酶和 Claudin1 的基因表达呈线性上调（p<0.05）。厚朴酚的添加对胴体特性或盲肠短链脂肪酸没有影响（p>0.05）。结果表明，厚朴酚可应用于肉鸡日粮中，以提高其抗氧化能力和肠道健康。
