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在 COVID-19 时代,二甲双胍相关的乳酸酸中毒和急性肾损伤。

Metformin-associated lactic acidosis and acute kidney injury in the era of COVID-19.

机构信息

Department of Nephrology, General Hospital of Nikaia-Piraeus, 18454 Athens, Greece.

出版信息

Front Biosci (Schol Ed). 2021 Dec 3;13(2):202-207. doi: 10.52586/S563.

Abstract

COVID-19, provoked by SARS-CoV-2, constitutes a global health issue with high rates of mortality. The presence of diabetes mellitus is associated with severe coronavirus COVID-19 as it is related to increased death rates in patients admitted to the intensive care unit. Acute kidney injury is a frequent complication among patients hospitalized for COVID-19 and is met with high morbidity and mortality. Here, we present a case of a diabetic patient with acute kidney injury, metformin-associated lactic acidosis, and COVID-19. Lactic acidosis is a relatively rare but noteworthy complication of metformin use. However, the combination of those life-threatening situations could prove fatal for the patients despite optimal medical care.

摘要

由 SARS-CoV-2 引发的 COVID-19 是一个具有高死亡率的全球健康问题。糖尿病与严重的冠状病毒 COVID-19 有关,因为它与入住重症监护病房的患者死亡率增加有关。急性肾损伤是 COVID-19 住院患者的常见并发症,具有高发病率和死亡率。在这里,我们介绍了一例糖尿病合并急性肾损伤、二甲双胍相关乳酸性酸中毒和 COVID-19 的患者。乳酸性酸中毒是二甲双胍使用中相对罕见但值得注意的并发症。然而,尽管进行了最佳的医疗护理,这些危及生命的情况的组合可能对患者致命。

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