Department of Bioinformatics, Central University of South Bihar, Gaya, India.
Department of Bioinformatics, Central University of South Bihar, Gaya, India.
Microbes Infect. 2022 Apr-May;24(3):104925. doi: 10.1016/j.micinf.2021.104925. Epub 2021 Dec 6.
Oral cancer contributes significantly to the global cancer burden. Oral bacteria play an important role in the spread of oral cancer, according to mounting evidence. The most proven instance is the carcinogenic implications of Porphyromonas gingivalis, a key pathogen in chronic periodontitis. It is imperative to understand the pathogenesis of P. gingivalis in OSCC. This review aims to gather and assess scientific shreds of evidence on the involvement of P. gingivalis in the molecular mechanism of oral squamous cell carcinoma.
口腔癌对全球癌症负担有重大影响。越来越多的证据表明，口腔细菌在口腔癌的传播中起着重要作用。最有说服力的例子是牙龈卟啉单胞菌（Porphyromonas gingivalis）的致癌作用，它是慢性牙周炎的关键病原体。了解 P. gingivalis 在口腔鳞状细胞癌（OSCC）中的发病机制至关重要。本综述旨在收集和评估关于 P. gingivalis 参与口腔鳞状细胞癌分子机制的科学证据。
