Takematsu H, Suzuki R, Tagami H, Kumagai K
Dermatologica. 1986;172(5):236-40. doi: 10.1159/000249347.
Interleukin-1 (IL-1)-like activity was assessed in scale extracts prepared from skin specimens from 36 cases of psoriasis and other dermatoses characterized by the formation of sterile subcorneal pustules. IL-1 activity was detected in only 2 samples. In contrast, much higher IL-1 activity was demonstrated in horny tissue extracts prepared either from normal skin or from noninflammatory skin such as plantar callus, scar or ichthyosis. No correlation was found between neutrophil chemotactic activity and IL-1 activity demonstrable in horny tissue extracts.
在从36例银屑病及其他以无菌性角层下脓疱形成为特征的皮肤病患者的皮肤标本制备的鳞屑提取物中评估了白细胞介素-1（IL-1）样活性。仅在2个样本中检测到IL-1活性。相比之下，在从正常皮肤或非炎性皮肤（如足底胼胝、瘢痕或鱼鳞病）制备的角质组织提取物中显示出更高的IL-1活性。在角质组织提取物中可检测到的中性粒细胞趋化活性与IL-1活性之间未发现相关性。
