Department of Environmental Sciences, University of California, Riverside, CA, USA.
Nicholas School of the Environment, Duke University, Durham, NC, USA.
Environ Res. 2022 Apr 1;205:112525. doi: 10.1016/j.envres.2021.112525. Epub 2021 Dec 8.
Organophosphate esters (OPEs) have been detected within car interior dust, suggesting that the indoor microenvironment of vehicles may represent a potential route of human exposure to OPEs. We recently showed that people with longer commutes are exposed to higher concentrations of tris(1,3-dichloro-2-isopropyl)phosphate (TDCIPP) - a widely used OPE - and other studies have suggested that dust removal may lead to lower exposure to chemicals. Therefore, the overall objective of this study was to determine if a decrease in interior car dust results in mitigation of personal OPE exposure. Participants (N = 49) were asked to wear silicone wristbands, and a subset of them wiped interior parts at the front of their vehicles prior to one study week (N = 25) or both study weeks (N = 11). There were no significant differences in total OPE concentrations (77.79-13,660 ng/g) nor individual OPE concentrations (0.04-4852.81 ng/g) across the different wiping groups nor in relation to participant residence ZIP codes and AC/Heater usage. These findings suggest that higher exposure to TDCIPP for participants with longer commutes may be independent of dust located on interior parts at the front of the vehicle. Therefore, our study demonstrates that there is a need for research on the potential contribution of other sources of TDCIPP exposure within car interiors.
有机磷酸酯 (OPEs) 已在汽车内部灰尘中被检测到,这表明车辆的室内微环境可能是人类接触 OPEs 的潜在途径。我们最近发现,通勤时间较长的人接触到的三(1,3-二氯-2-异丙基)磷酸酯 (TDCIPP) 的浓度更高,这是一种广泛使用的 OPE,其他研究表明,清除灰尘可能会导致接触化学物质的风险降低。因此,本研究的总体目标是确定减少汽车内部灰尘是否会减轻个人接触 OPE 的程度。参与者(N=49)被要求佩戴硅树脂腕带,其中一部分人在研究周的前一周(N=25)或两周都(N=11)擦拭车辆前部的内饰。不同擦拭组之间,以及参与者居住的邮政编码和空调/暖气使用情况与总 OPE 浓度(77.79-13660ng/g)或个别 OPE 浓度(0.04-4852.81ng/g)均无显著差异。这些发现表明,对于通勤时间较长的参与者来说,更高的 TDCIPP 暴露可能与车辆前部内饰上的灰尘无关。因此,我们的研究表明,需要研究汽车内饰中其他 TDCIPP 暴露源的潜在贡献。