• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The Potential Anti-Inflammatory Effects of Zerumbone in COVID-19 Patients.

作者信息

Dehghan Razieh, Soheilifar Mohammad Hasan, Azizi Jalilian Farid, Najafi Rezvan, Amini Razieh

机构信息

Research Center for Molecular Medicine, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Department of Medical Laser, Medical Laser Research Center, Yara Institute, ACECR, Tehran, Iran.

出版信息

Avicenna J Med Biotechnol. 2021 Oct-Dec;13(4):234-236.

PMID:34900152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8606107/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85a/8606107/ee6b9a06d949/AJMB-13-234-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85a/8606107/ee6b9a06d949/AJMB-13-234-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f85a/8606107/ee6b9a06d949/AJMB-13-234-g001.jpg

相似文献

1
The Potential Anti-Inflammatory Effects of Zerumbone in COVID-19 Patients.姜黄二酮对新冠肺炎患者的潜在抗炎作用
Avicenna J Med Biotechnol. 2021 Oct-Dec;13(4):234-236.
2
Zerumbone ameliorates behavioral impairments and neuropathology in transgenic APP/PS1 mice by suppressing MAPK signaling.小豆蔻明通过抑制 MAPK 信号通路改善转 APP/PS1 小鼠的行为损伤和神经病理学。
J Neuroinflammation. 2020 Feb 17;17(1):61. doi: 10.1186/s12974-020-01744-1.
3
Antinociceptive and Anti-Inflammatory Effects of Zerumbone against Mono-Iodoacetate-Induced Arthritis.莪术酮对单碘乙酸盐诱导的关节炎的镇痛和抗炎作用。
Int J Mol Sci. 2016 Feb 18;17(2):249. doi: 10.3390/ijms17020249.
4
Possible Contribution of Zerumbone-Induced Proteo-Stress to Its Anti-Inflammatory Functions via the Activation of Heat Shock Factor 1.姜酮诱导的蛋白质应激通过激活热休克因子1对其抗炎功能的潜在贡献。
PLoS One. 2016 Aug 18;11(8):e0161282. doi: 10.1371/journal.pone.0161282. eCollection 2016.
5
Zerumbone Modulates α-Adrenergic, TRPV1, and NMDA NR2B Receptors Plasticity in CCI-Induced Neuropathic Pain and LPS-Induced SH-SY5Y Neuroblastoma Models.姜烯酮对CCI诱导的神经性疼痛模型和LPS诱导的SH-SY5Y神经母细胞瘤模型中的α-肾上腺素能、TRPV1和NMDA NR2B受体可塑性具有调节作用。
Front Pharmacol. 2020 Mar 4;11:92. doi: 10.3389/fphar.2020.00092. eCollection 2020.
6
Zerumbone Suppresses Enterotoxigenic Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ.姜烯酮通过抑制 NF-κΒ 抑制肠毒素感染诱导的结肠炎症。
Int J Mol Sci. 2019 Sep 14;20(18):4560. doi: 10.3390/ijms20184560.
7
Immunomodulation of Zerumbone via Decreasing the Production of Reactive Oxygen Species from Immune Cells.通过减少免疫细胞活性氧的产生实现姜黄二酮的免疫调节作用。
Pak J Biol Sci. 2018 Jan;21(9):475-479. doi: 10.3923/pjbs.2018.475.479.
8
Anti-biofilm and anti-virulence effects of zerumbone against .姜烯酮对 的抗生物膜和抗毒力作用。
Microbiology (Reading). 2020 Aug;166(8):717-726. doi: 10.1099/mic.0.000930.
9
Zerumbone Suppresses the LPS-Induced Inflammatory Response and Represses Activation of the NLRP3 Inflammasome in Macrophages.姜酮抑制巨噬细胞中脂多糖诱导的炎症反应并抑制NLRP3炎性小体的激活。
Front Pharmacol. 2021 May 11;12:652860. doi: 10.3389/fphar.2021.652860. eCollection 2021.
10
Zerumbone exerts a beneficial effect on inflammatory parameters of cholecystokinin octapeptide-induced experimental pancreatitis but fails to improve histology.姜酮对胆囊收缩素八肽诱导的实验性胰腺炎的炎症参数具有有益作用，但未能改善组织学。
Pancreas. 2007 Oct;35(3):249-55. doi: 10.1097/mpa.0b013e318070d791.

引用本文的文献

1
Flavonoids of Euphorbia hirta inhibit inflammatory mechanisms via Nrf2 and NF-κB pathways.飞扬草的黄酮类化合物通过Nrf2和NF-κB途径抑制炎症机制。
Cell Biochem Biophys. 2025 Mar;83(1):1167-1183. doi: 10.1007/s12013-024-01551-y. Epub 2024 Nov 6.
2
The protective effects of Zingiber zerumbet rhizome against fevers in rats.菖蒲根茎防治大鼠发热的保护作用。
Naturwissenschaften. 2024 Apr 1;111(2):20. doi: 10.1007/s00114-024-01907-7.

本文引用的文献

1
Hypoxia: A key feature of COVID-19 launching activation of HIF-1 and cytokine storm.缺氧：新冠病毒病的一个关键特征，引发缺氧诱导因子-1激活和细胞因子风暴。
J Inflamm (Lond). 2020 Oct 29;17:33. doi: 10.1186/s12950-020-00263-3. eCollection 2020.
2
Immune Response, Inflammation, and the Clinical Spectrum of COVID-19.免疫反应、炎症与 COVID-19 的临床谱。
Front Immunol. 2020 Jun 16;11:1441. doi: 10.3389/fimmu.2020.01441. eCollection 2020.
3
Targeting inflammation and cytokine storm in COVID-19.针对新型冠状病毒肺炎中的炎症和细胞因子风暴
Pharmacol Res. 2020 Sep;159:105051. doi: 10.1016/j.phrs.2020.105051. Epub 2020 Jun 27.
4
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.宿主对 SARS-CoV-2 的失衡反应导致 COVID-19 的发生。
Cell. 2020 May 28;181(5):1036-1045.e9. doi: 10.1016/j.cell.2020.04.026. Epub 2020 May 15.
5
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages.COVID-19 患者的病理性炎症：单核细胞和巨噬细胞的关键作用。
Nat Rev Immunol. 2020 Jun;20(6):355-362. doi: 10.1038/s41577-020-0331-4. Epub 2020 May 6.
6
Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19.SARS-CoV-2 和 SARS-CoV 在人肺中的比较复制和免疫激活特征：一项具有 COVID-19 发病机制意义的离体研究。
Clin Infect Dis. 2020 Sep 12;71(6):1400-1409. doi: 10.1093/cid/ciaa410.
7
Zerumbone Suppresses Enterotoxigenic Infection-Induced Colonic Inflammation through Inhibition of NF-κΒ.姜烯酮通过抑制 NF-κΒ 抑制肠毒素感染诱导的结肠炎症。
Int J Mol Sci. 2019 Sep 14;20(18):4560. doi: 10.3390/ijms20184560.
8
Zerumbone suppresses the activation of inflammatory mediators in LPS-stimulated U937 macrophages through MyD88-dependent NF-κB/MAPK/PI3K-Akt signaling pathways.姜烯酮通过 MyD88 依赖的 NF-κB/MAPK/PI3K-Akt 信号通路抑制 LPS 刺激的 U937 巨噬细胞中炎症介质的激活。
Int Immunopharmacol. 2018 Feb;55:312-322. doi: 10.1016/j.intimp.2018.01.001. Epub 2018 Jan 5.
9
Antiallodynic and antihyperalgesic activities of zerumbone via the suppression of IL-1β, IL-6, and TNF-α in a mouse model of neuropathic pain.在神经性疼痛小鼠模型中，莪术二酮通过抑制白细胞介素-1β、白细胞介素-6和肿瘤坏死因子-α发挥抗痛觉过敏和抗痛觉超敏作用。
J Pain Res. 2017 Nov 8;10:2605-2619. doi: 10.2147/JPR.S143024. eCollection 2017.
10
Antinociceptive and Anti-Inflammatory Effects of Zerumbone against Mono-Iodoacetate-Induced Arthritis.莪术酮对单碘乙酸盐诱导的关节炎的镇痛和抗炎作用。
Int J Mol Sci. 2016 Feb 18;17(2):249. doi: 10.3390/ijms17020249.