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Most cases of Thrombosis and Thrombocytopenia Syndrome (TTS) post ChAdOx-1 nCov-19 are Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT).大多数接种ChAdOx-1 nCov-19疫苗后出现的血栓形成和血小板减少综合征（TTS）病例为疫苗诱导的免疫性血栓性血小板减少症（VITT）。
Lancet Reg Health Eur. 2021 Nov 29;12:100274. doi: 10.1016/j.lanepe.2021.100274. eCollection 2022 Jan.
2
Laboratory confirmed vaccine-induced immune thrombotic thrombocytopenia: Retrospective analysis of reported cases after vaccination with ChAdOx-1 nCoV-19 in Germany.实验室确诊的疫苗诱导免疫性血栓性血小板减少症：德国接种ChAdOx-1 nCoV-19疫苗后报告病例的回顾性分析
Lancet Reg Health Eur. 2022 Jan;12:100270. doi: 10.1016/j.lanepe.2021.100270. Epub 2021 Dec 6.
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Res Pract Thromb Haemost. 2023 Oct 31;7(8):102243. doi: 10.1016/j.rpth.2023.102243. eCollection 2023 Nov.
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A case report of vaccine-induced immune thrombotic thrombocytopenia (VITT) with genetic analysis.一例疫苗诱导的免疫性血栓性血小板减少症（VITT）病例报告及基因分析
Front Cardiovasc Med. 2023 May 19;10:1189320. doi: 10.3389/fcvm.2023.1189320. eCollection 2023.
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Vaccine-induced immune thrombotic thrombocytopenia: what do we know hitherto?疫苗诱导的免疫性血栓性血小板减少症：我们目前了解多少？
Front Med (Lausanne). 2023 May 16;10:1155727. doi: 10.3389/fmed.2023.1155727. eCollection 2023.
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How to approach acute thrombosis and thrombocytopenia.如何处理急性血栓和血小板减少症。
Clin Med (Lond). 2023 May;23(3):234-241. doi: 10.7861/clinmed2023-0076.
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Risk assessment of retinal vascular occlusion after COVID-19 vaccination.新冠疫苗接种后视网膜血管阻塞的风险评估
NPJ Vaccines. 2023 May 2;8(1):64. doi: 10.1038/s41541-023-00661-7.
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Thrombosis with Thrombocytopenia Syndrome (TTS) After ChAdOx1 nCoV-19 Immunization: An Investigative Case Report.腺病毒载体新冠疫苗（ChAdOx1 nCoV-19）接种后发生伴血小板减少的血栓形成综合征（TTS）：一项调查性病例报告。
Am J Case Rep. 2023 Mar 18;24:e938878. doi: 10.12659/AJCR.938878.

本文引用的文献

1
Laboratory confirmed vaccine-induced immune thrombotic thrombocytopenia: Retrospective analysis of reported cases after vaccination with ChAdOx-1 nCoV-19 in Germany.实验室确诊的疫苗诱导免疫性血栓性血小板减少症：德国接种ChAdOx-1 nCoV-19疫苗后报告病例的回顾性分析
Lancet Reg Health Eur. 2022 Jan;12:100270. doi: 10.1016/j.lanepe.2021.100270. Epub 2021 Dec 6.
2
Vaccine-Induced Thrombocytopenia with Severe Headache.疫苗诱导的血小板减少症伴严重头痛
N Engl J Med. 2021 Nov 25;385(22):2103-2105. doi: 10.1056/NEJMc2112974. Epub 2021 Sep 15.
3
Clinical Features of Vaccine-Induced Immune Thrombocytopenia and Thrombosis.疫苗诱导的免疫性血小板减少症和血栓形成的临床特征。
N Engl J Med. 2021 Oct 28;385(18):1680-1689. doi: 10.1056/NEJMoa2109908. Epub 2021 Aug 11.
4
Evaluation of laboratory assays for anti-platelet factor 4 antibodies after ChAdOx1 nCOV-19 vaccination.评价 ChAdOx1 nCOV-19 疫苗接种后抗血小板因子 4 抗体的实验室检测。
J Thromb Haemost. 2021 Aug;19(8):2007-2013. doi: 10.1111/jth.15362. Epub 2021 Jul 5.
5
Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination.接种 ChAdOx1 nCov-19 疫苗后发生血栓性血小板减少症。
N Engl J Med. 2021 Jun 3;384(22):2092-2101. doi: 10.1056/NEJMoa2104840. Epub 2021 Apr 9.
6
CLINICAL PRACTICE. Heparin-Induced Thrombocytopenia.临床实践。肝素诱导的血小板减少症。
N Engl J Med. 2015 Jul 16;373(3):252-61. doi: 10.1056/NEJMcp1411910.

Most cases of Thrombosis and Thrombocytopenia Syndrome (TTS) post ChAdOx-1 nCov-19 are Vaccine-induced Immune Thrombotic Thrombocytopenia (VITT).

作者信息

Makris Michael, Pavord Sue

机构信息

Department of Infection, Immunity and Cardiovascular Disease (IICD), University of Sheffield, United Kingdom.

Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

出版信息

Lancet Reg Health Eur. 2021 Nov 29;12:100274. doi: 10.1016/j.lanepe.2021.100274. eCollection 2022 Jan.

DOI:10.1016/j.lanepe.2021.100274
PMID:34901913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8639457/
Abstract
摘要